3-Amino-2-fluorobenzoic Acid

Name: 3-Amino-2-fluorobenzoic Acid
Brand: Vaqora Chemicals
SKU: VQ-050958

About 3-Amino-2-fluorobenzoic Acid

Listed under CAS 914223-43-1, 3-Amino-2-fluorobenzoic Acid is a process intermediate or related compound of Dabrafenib available from Vaqora Chemicals. Its molecular formula is C7H6FNO2 and its molecular weight is 155.13 g/mol. Common synonyms include Benzoicacid, 3-amino-2-fluoro- and Benzoic acid, 3-amino-2-fluoro-.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Dabrafenib, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 3-Amino-2-fluorobenzoic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Dabrafenib

View every impurity, metabolite and intermediate we list for Dabrafenib.

Dabrafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Amino-2-fluorobenzoic Acid
Catalogue No.	VQ-050958
CAS Number	914223-43-1
IUPAC name	3-amino-2-fluorobenzoic acid
Molecular formula	C₇H₆FNO₂
Molecular weight	155.13 g/mol
Exact mass	155.0383
HSN code	2933
InChIKey	WZCZMWMNVHEBCK-UHFFFAOYSA-N
SMILES	C1=CC(=C(C(=C1)N)F)C(=O)O
PubChem CID	23094343

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	2 / 4
TPSA	63.3 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Amino-2-fluorobenzoic Acid?

The CAS Registry Number of 3-Amino-2-fluorobenzoic Acid is 914223-43-1. It is also known as Benzoicacid, 3-amino-2-fluoro-, Benzoic acid, 3-amino-2-fluoro-, 2-fluoro-3-aminobenzoic acid.

What is the molecular formula and molecular weight of 3-Amino-2-fluorobenzoic Acid?

3-Amino-2-fluorobenzoic Acid has the molecular formula C7H6FNO2 and a molecular weight of 155.13 g/mol. Its IUPAC name is 3-amino-2-fluorobenzoic acid.

What is 3-Amino-2-fluorobenzoic Acid used for?

3-Amino-2-fluorobenzoic Acid is supplied as a characterised reference material related to Dabrafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Amino-2-fluorobenzoic Acid can I order?

We supply 3-Amino-2-fluorobenzoic Acid, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Amino-2-fluorobenzoic Acid?

Yes. Every lot of 3-Amino-2-fluorobenzoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Amino-2-fluorobenzoic Acid be shipped internationally?

Yes. 3-Amino-2-fluorobenzoic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.