4-Fluoro-3-nitro-benzenesulfonyl Chloride

Name: 4-Fluoro-3-nitro-benzenesulfonyl Chloride
Brand: Vaqora Chemicals
SKU: VQ-049941

About 4-Fluoro-3-nitro-benzenesulfonyl Chloride

4-Fluoro-3-nitro-benzenesulfonyl Chloride (CAS 6668-56-0) is an impurity of Dabrafenib offered by Vaqora Chemicals. The compound has the formula C6H3ClFNO4S, corresponding to a molecular weight of 239.61 g/mol. It is also known as 4-Fluoro-3-nitrobenzenesulphonyl chloride or Benzenesulfonyl chloride, 4-fluoro-3-nitro-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Dabrafenib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 4-Fluoro-3-nitro-benzenesulfonyl Chloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dabrafenib

View every impurity, metabolite and intermediate we list for Dabrafenib.

Dabrafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Fluoro-3-nitro-benzenesulfonyl Chloride
Catalogue No.	VQ-049941
CAS Number	6668-56-0
IUPAC name	4-fluoro-3-nitrobenzenesulfonyl chloride
Molecular formula	C₆H₃ClFNO₄S
Molecular weight	239.61 g/mol
Exact mass	238.9455
Grade	Reference Standard
HSN code	38229090
InChIKey	RRONENSZKCGROA-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1S(=O)(=O)Cl)[N+](=O)[O-])F
PubChem CID	2782799

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	0 / 5
TPSA	88.3 Å²
Synonyms	4-Fluoro-3-nitrobenzenesulphonyl chloride, Benzenesulfonyl chloride, 4-fluoro-3-nitro-, chloro(4-fluoro-3-nitrophenyl)sulfone, 4-Fluoro-3-nitrophenylsulfonyl chloride, 5-(Chlorosulphonyl)-2-fluoronitrobenzene, 4-fluoro-3-nitrobenzenesulfonyl chloride, AldrichCPR

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P260, P261, P264, P264 + P265, P271, P280, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P317, P319, P321, P363, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Fluoro-3-nitro-benzenesulfonyl Chloride?

The CAS Registry Number of 4-Fluoro-3-nitro-benzenesulfonyl Chloride is 6668-56-0. It is also known as 4-Fluoro-3-nitrobenzenesulphonyl chloride, Benzenesulfonyl chloride, 4-fluoro-3-nitro-, chloro(4-fluoro-3-nitrophenyl)sulfone.

What is the molecular formula and molecular weight of 4-Fluoro-3-nitro-benzenesulfonyl Chloride?

4-Fluoro-3-nitro-benzenesulfonyl Chloride has the molecular formula C6H3ClFNO4S and a molecular weight of 239.61 g/mol. Its IUPAC name is 4-fluoro-3-nitrobenzenesulfonyl chloride.

What is 4-Fluoro-3-nitro-benzenesulfonyl Chloride used for?

4-Fluoro-3-nitro-benzenesulfonyl Chloride is supplied as a characterised reference material related to Dabrafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Fluoro-3-nitro-benzenesulfonyl Chloride can I order?

We supply 4-Fluoro-3-nitro-benzenesulfonyl Chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Fluoro-3-nitro-benzenesulfonyl Chloride?

Yes. Every lot of 4-Fluoro-3-nitro-benzenesulfonyl Chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Fluoro-3-nitro-benzenesulfonyl Chloride be shipped internationally?

Yes. 4-Fluoro-3-nitro-benzenesulfonyl Chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.