Nilotinib 3-Imidazolyl N-oxide

Name: Nilotinib 3-Imidazolyl N-oxide
Brand: Vaqora Chemicals
SKU: VQ-023257

About Nilotinib 3-Imidazolyl N-oxide

Listed under CAS 2139382-75-3, Nilotinib 3-Imidazolyl N-oxide is a metabolite or degradation product of Nilotinib available from Vaqora Chemicals. The compound has the formula C28H22F3N7O2, corresponding to a molecular weight of 545.5 g/mol. Common synonyms include Nilotinib Imidazolyl N-oxide and Nilotinib N-Oxide (Imidazole N-Oxide).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Nilotinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nilotinib 3-Imidazolyl N-oxide
Catalogue No.	VQ-023257
CAS Number	2139382-75-3
IUPAC name	4-methyl-N-[3-(4-methyl-3-oxidoimidazol-3-ium-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
Molecular formula	C₂₈H₂₂F₃N₇O₂
Molecular weight	545.5 g/mol
Exact mass	545.1787
Grade	Reference Standard
HSN code	38229090
InChIKey	ZKPCDROOIRRXJU-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C([N+](=C3)[O-])C)NC4=NC=CC(=N4)C5=CN=CC=C5
PubChem CID	154789980

Physical properties
Physical form	Solid
LogP (XLogP3)	4.6
H-bond donors / acceptors	2 / 9
TPSA	110 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nilotinib 3-Imidazolyl N-oxide?

The CAS Registry Number of Nilotinib 3-Imidazolyl N-oxide is 2139382-75-3. It is also known as Nilotinib Imidazolyl N-oxide, Nilotinib N-Oxide (Imidazole N-Oxide).

What is the molecular formula and molecular weight of Nilotinib 3-Imidazolyl N-oxide?

Nilotinib 3-Imidazolyl N-oxide has the molecular formula C28H22F3N7O2 and a molecular weight of 545.5 g/mol. Its IUPAC name is 4-methyl-N-[3-(4-methyl-3-oxidoimidazol-3-ium-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide.

What is Nilotinib 3-Imidazolyl N-oxide used for?

Nilotinib 3-Imidazolyl N-oxide is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nilotinib 3-Imidazolyl N-oxide can I order?

We supply Nilotinib 3-Imidazolyl N-oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nilotinib 3-Imidazolyl N-oxide?

Yes. Every lot of Nilotinib 3-Imidazolyl N-oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nilotinib 3-Imidazolyl N-oxide be shipped internationally?

Yes. We export Nilotinib 3-Imidazolyl N-oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.