Nilotinib N-Oxide

Name: Nilotinib N-Oxide
Brand: Vaqora Chemicals
SKU: VQ-026907

About Nilotinib N-Oxide

Listed under CAS 1246817-85-5, Nilotinib N-Oxide is a metabolite or degradation product of Nilotinib available from Vaqora Chemicals. Its molecular formula is C28H22F3N7O2 and its molecular weight is 545.5 g/mol. Common synonyms include Nilotinib Pyridine N-Oxide and Imidazole N-Oxide.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Nilotinib, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Nilotinib N-Oxide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nilotinib N-Oxide
Catalogue No.	VQ-026907
CAS Number	1246817-85-5
IUPAC name	4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(1-oxidopyridin-1-ium-3-yl)pyrimidin-2-yl]amino]benzamide
Molecular formula	C₂₈H₂₂F₃N₇O₂
Molecular weight	545.5 g/mol
Exact mass	545.1787
Grade	Reference Standard
HSN code	38229090
InChIKey	OGMQYIIDZDUGEY-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=C[N+](=CC=C5)[O-]
PubChem CID	71750948

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	2 / 9
TPSA	110 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nilotinib N-Oxide?

The CAS Registry Number of Nilotinib N-Oxide is 1246817-85-5. It is also known as Nilotinib Pyridine N-Oxide, Imidazole N-Oxide, BEJ-866.

What is the molecular formula and molecular weight of Nilotinib N-Oxide?

Nilotinib N-Oxide has the molecular formula C28H22F3N7O2 and a molecular weight of 545.5 g/mol. Its IUPAC name is 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(1-oxidopyridin-1-ium-3-yl)pyrimidin-2-yl]amino]benzamide.

What is Nilotinib N-Oxide used for?

Nilotinib N-Oxide is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nilotinib N-Oxide can I order?

We supply Nilotinib N-Oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nilotinib N-Oxide?

Yes. Every lot of Nilotinib N-Oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nilotinib N-Oxide be shipped internationally?

Yes. We export Nilotinib N-Oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.