3-Ethoxy-4-methoxybenzonitrile

Name: 3-Ethoxy-4-methoxybenzonitrile
Brand: Vaqora Chemicals
SKU: VQ-013021

About 3-Ethoxy-4-methoxybenzonitrile

Listed under CAS 60758-86-3, 3-Ethoxy-4-methoxybenzonitrile is a process intermediate or related compound of Apremilast available from Vaqora Chemicals. The compound has the formula C10H11NO2, corresponding to a molecular weight of 177.2 g/mol. Common synonyms include 3-ethoxy-4-methoxy-benzonitrile and Benzonitrile, 3-ethoxy-4-methoxy-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 6 hazard statements. Review the Safety Data Sheet before use.

Process chemists and analysts use it when developing synthetic routes to Apremilast, tracking process-related impurities and validating analytical methods. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 3-Ethoxy-4-methoxybenzonitrile in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Apremilast

View every impurity, metabolite and intermediate we list for Apremilast.

Apremilast impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Ethoxy-4-methoxybenzonitrile
Catalogue No.	VQ-013021
CAS Number	60758-86-3
IUPAC name	3-ethoxy-4-methoxybenzonitrile
Molecular formula	C₁₀H₁₁NO₂
Molecular weight	177.2 g/mol
Exact mass	177.079
Grade	Reference Standard
HSN code	2933
InChIKey	XTIINWPNAMHVDG-UHFFFAOYSA-N
SMILES	CCOC1=C(C=CC(=C1)C#N)OC
PubChem CID	3934769

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	0 / 3
TPSA	42.3 Å²
Synonyms	3-ethoxy-4-methoxy-benzonitrile, Benzonitrile, 3-ethoxy-4-methoxy-, CS-M3350, 3-ethoxy-4-methoxybenzenecarbonitrile, 3-Ethoxy-4-Methoxy Benzonitrile

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301+H311+H331Toxic if swallowed, in contact with skin or if inhaled
H301Toxic if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled

Precautionary statements: P261, P262, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Ethoxy-4-methoxybenzonitrile?

The CAS Registry Number of 3-Ethoxy-4-methoxybenzonitrile is 60758-86-3. It is also known as 3-ethoxy-4-methoxy-benzonitrile, Benzonitrile, 3-ethoxy-4-methoxy-, CS-M3350.

What is the molecular formula and molecular weight of 3-Ethoxy-4-methoxybenzonitrile?

3-Ethoxy-4-methoxybenzonitrile has the molecular formula C10H11NO2 and a molecular weight of 177.2 g/mol. Its IUPAC name is 3-ethoxy-4-methoxybenzonitrile.

What is 3-Ethoxy-4-methoxybenzonitrile used for?

3-Ethoxy-4-methoxybenzonitrile is supplied as a characterised reference material related to Apremilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Ethoxy-4-methoxybenzonitrile can I order?

We supply 3-Ethoxy-4-methoxybenzonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Ethoxy-4-methoxybenzonitrile?

Yes. Every lot of 3-Ethoxy-4-methoxybenzonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Ethoxy-4-methoxybenzonitrile be shipped internationally?

Yes. 3-Ethoxy-4-methoxybenzonitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.