4-(Acetylamino)phthalic Anhydride

Name: 4-(Acetylamino)phthalic Anhydride
Brand: Vaqora Chemicals
SKU: VQ-013065

About 4-(Acetylamino)phthalic Anhydride

Listed under CAS 22235-04-7, 4-(Acetylamino)phthalic Anhydride is a process intermediate or related compound of Apremilast available from Vaqora Chemicals at a purity of 93.40%. With the molecular formula C10H7NO4, it has a molar mass of 205.17 g/mol. Systematically, it is named N-(1,3-dioxo-2-benzofuran-5-yl)acetamide. It is also known as 4-(Acetylamino)phthalicanhydride or N-(1,3-dioxoisobenzofuran-5-yl)acetamide.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is a process intermediate or related compound in the synthesis of Apremilast, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Apremilast

View every impurity, metabolite and intermediate we list for Apremilast.

Apremilast impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(Acetylamino)phthalic Anhydride
Catalogue No.	VQ-013065
CAS Number	22235-04-7
IUPAC name	N-(1,3-dioxo-2-benzofuran-5-yl)acetamide
Molecular formula	C₁₀H₇NO₄
Molecular weight	205.17 g/mol
Exact mass	205.0375
Grade	Reference Standard
Purity / assay	93.40%
HSN code	2933
InChIKey	PFYOXMCPLCYYAQ-UHFFFAOYSA-N
SMILES	CC(=O)NC1=CC2=C(C=C1)C(=O)OC2=O
PubChem CID	11229489

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	1 / 4
TPSA	72.5 Å²
Synonyms	N-(1,3-Dihydro-1,3-dioxo-5-isobenzofuranyl)acetamide, 4-(Acetylamino)phthalicanhydride, N-(1,3-Dioxo-1,3-dihydroisobenzofuran-5-yl)acetamide, N-(1,3-dioxo-1,3-dihydro-2-benzofuran-5-yl)acetamide, N-(1,3-dioxoisobenzofuran-5-yl)acetamide, 4-acetamidophthalic anhydride

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(Acetylamino)phthalic Anhydride?

The CAS Registry Number of 4-(Acetylamino)phthalic Anhydride is 22235-04-7. It is also known as N-(1,3-Dihydro-1,3-dioxo-5-isobenzofuranyl)acetamide, 4-(Acetylamino)phthalicanhydride, N-(1,3-Dioxo-1,3-dihydroisobenzofuran-5-yl)acetamide.

What is the molecular formula and molecular weight of 4-(Acetylamino)phthalic Anhydride?

4-(Acetylamino)phthalic Anhydride has the molecular formula C10H7NO4 and a molecular weight of 205.17 g/mol. Its IUPAC name is N-(1,3-dioxo-2-benzofuran-5-yl)acetamide.

What is 4-(Acetylamino)phthalic Anhydride used for?

4-(Acetylamino)phthalic Anhydride is supplied as a characterised reference material related to Apremilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(Acetylamino)phthalic Anhydride can I order?

We supply 4-(Acetylamino)phthalic Anhydride in Reference Standard (93.40%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(Acetylamino)phthalic Anhydride?

Yes. Every lot of 4-(Acetylamino)phthalic Anhydride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(Acetylamino)phthalic Anhydride be shipped internationally?

Yes. We export 4-(Acetylamino)phthalic Anhydride worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.