N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)ac… 6296-53-3

Name: N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide
Brand: Vaqora Chemicals
SKU: VQ-013582

About N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide

N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide is a process intermediate or related compound of Apremilast carrying the CAS registry number 6296-53-3. With the molecular formula C10H7NO4, it has a molar mass of 205.17 g/mol. The IUPAC name is N-(1,3-dioxo-2-benzofuran-4-yl)acetamide. It is also known as 3-Acetamidophthalic anhydride or 3-Acetoamidophthalic anhydride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Apremilast, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Apremilast

View every impurity, metabolite and intermediate we list for Apremilast.

Apremilast impurities

Specifications & identifiers

Chemical identifiers
Product name	N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide
Catalogue No.	VQ-013582
CAS Number	6296-53-3
IUPAC name	N-(1,3-dioxo-2-benzofuran-4-yl)acetamide
Molecular formula	C₁₀H₇NO₄
Molecular weight	205.17 g/mol
Exact mass	205.0375
Grade	Reference Standard
HSN code	2933
InChIKey	PAUAJOABXCGLCN-UHFFFAOYSA-N
SMILES	CC(=O)NC1=CC=CC2=C1C(=O)OC2=O
PubChem CID	226121

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	1 / 4
TPSA	72.5 Å²
Synonyms	N-(1,3-Dihydro-1,3-dioxo-4-isobenzofuranyl)acetamide, 3-Acetamidophthalic anhydride, 3-Acetoamidophthalic anhydride, 3-Acetylaminophthalic anhydride, N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide, 1,3-Dioxo-2-isoindolineaceticacid, 4-Acetamido-1,3-isobenzofurandione, N-(1,3-dioxo-1,3-dihydroisobenzo[b]furan-4-yl)acetamide, Acetamide, N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)-, AcetaMide,N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl), 3-Acetamidophthalicanhydride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P261, P264, P264 + P265, P271, P273, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide?

The CAS Registry Number of N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide is 6296-53-3. It is also known as N-(1,3-Dihydro-1,3-dioxo-4-isobenzofuranyl)acetamide, 3-Acetamidophthalic anhydride, 3-Acetoamidophthalic anhydride.

What is the molecular formula and molecular weight of N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide?

N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide has the molecular formula C10H7NO4 and a molecular weight of 205.17 g/mol. Its IUPAC name is N-(1,3-dioxo-2-benzofuran-4-yl)acetamide.

What is N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide used for?

N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide is supplied as a characterised reference material related to Apremilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide can I order?

We supply N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide?

Yes. Every lot of N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide be shipped internationally?

Yes. N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.