3,4-Bis(Difluoromethoxy) Roflumilast

Name: 3,4-Bis(Difluoromethoxy) Roflumilast
Brand: Vaqora Chemicals
SKU: VQ-027880

About 3,4-Bis(Difluoromethoxy) Roflumilast

3,4-Bis(Difluoromethoxy) Roflumilast is an impurity of Roflumilast carrying the CAS registry number 162401-30-1. The compound has the formula C14H8Cl2F4N2O3, corresponding to a molecular weight of 399.1 g/mol. Its systematic (IUPAC) name is N-(3,5-dichloro-4-pyridinyl)-3,4-bis(difluoromethoxy)benzamide. It is also known as Roflumilast-5.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Roflumilast impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Roflumilast

View every impurity, metabolite and intermediate we list for Roflumilast.

Roflumilast impurities

Specifications & identifiers

Chemical identifiers
Product name	3,4-Bis(Difluoromethoxy) Roflumilast
Catalogue No.	VQ-027880
CAS Number	162401-30-1
IUPAC name	N-(3,5-dichloro-4-pyridinyl)-3,4-bis(difluoromethoxy)benzamide
Molecular formula	C₁₄H₈Cl₂F₄N₂O₃
Molecular weight	399.1 g/mol
Exact mass	397.9848
Grade	Reference Standard
HSN code	38229090
InChIKey	OIYBMFARPXRQBW-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1C(=O)NC2=C(C=NC=C2Cl)Cl)OC(F)F)OC(F)F
PubChem CID	19705425

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	1 / 8
TPSA	60.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3,4-Bis(Difluoromethoxy) Roflumilast?

The CAS Registry Number of 3,4-Bis(Difluoromethoxy) Roflumilast is 162401-30-1. It is also known as N-(3,5-dichloropyridin-4-yl)-3,4-bis(difluoromethoxy)benzamide, Benzamide, N-(3,5-dichloro-4-pyridinyl)-3,4-bis(difluoromethoxy)-, Roflumilast-5.

What is the molecular formula and molecular weight of 3,4-Bis(Difluoromethoxy) Roflumilast?

3,4-Bis(Difluoromethoxy) Roflumilast has the molecular formula C14H8Cl2F4N2O3 and a molecular weight of 399.1 g/mol. Its IUPAC name is N-(3,5-dichloro-4-pyridinyl)-3,4-bis(difluoromethoxy)benzamide.

What is 3,4-Bis(Difluoromethoxy) Roflumilast used for?

3,4-Bis(Difluoromethoxy) Roflumilast is supplied as a characterised reference material related to Roflumilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3,4-Bis(Difluoromethoxy) Roflumilast can I order?

We supply 3,4-Bis(Difluoromethoxy) Roflumilast in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3,4-Bis(Difluoromethoxy) Roflumilast?

Yes. Every lot of 3,4-Bis(Difluoromethoxy) Roflumilast is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3,4-Bis(Difluoromethoxy) Roflumilast be shipped internationally?

Yes. We export 3,4-Bis(Difluoromethoxy) Roflumilast worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.