Roflumilast N-oxide

Name: Roflumilast N-oxide
Brand: Vaqora Chemicals
SKU: VQ-023671

About Roflumilast N-oxide

Listed under CAS 292135-78-5, Roflumilast N-oxide is a metabolite or degradation product of Roflumilast available from Vaqora Chemicals. The compound has the formula C17H14Cl2F2N2O4, corresponding to a molecular weight of 419.2 g/mol. Systematically, it is named 3-(cyclopropylmethoxy)-N-(3,5-dichloro-1-hydroxy-4-pyridinylidene)-4-(difluoromethoxy)benzamide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Roflumilast, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Roflumilast N-oxide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Roflumilast

View every impurity, metabolite and intermediate we list for Roflumilast.

Roflumilast impurities

Specifications & identifiers

Chemical identifiers
Product name	Roflumilast N-oxide
Catalogue No.	VQ-023671
CAS Number	292135-78-5
IUPAC name	3-(cyclopropylmethoxy)-N-(3,5-dichloro-1-hydroxy-4-pyridinylidene)-4-(difluoromethoxy)benzamide
Molecular formula	C₁₇H₁₄Cl₂F₂N₂O₄
Molecular weight	419.2 g/mol
Exact mass	418.0299
Grade	Reference Standard
HSN code	38229090
InChIKey	KHXXMSARUQULRI-UHFFFAOYSA-N
SMILES	C1CC1COC2=C(C=CC(=C2)C(=O)N=C3C(=CN(C=C3Cl)O)Cl)OC(F)F
PubChem CID	9940999

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	1 / 7
TPSA	71.4 Å²
Synonyms	3,5-Dichloro-4-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamido)pyridine 1-oxide, 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-1-oxido-4-pyridinyl)-4-(difluoromethoxy)benzamide, N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-cyclopropylmethoxybenzamide, n-(3.5-dichloro-1-oxido-pyridin-4-yl)-4-difluoromethoxy-3-cyclopropylmethoxybenzamide, 3,5-Dichloro-4-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamido)pyridine1-oxide, 3, 5-dichloro-4-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamido)pyridine 1-oxide, 3,5-dichloro-4-(3-(cyclopropylmethoxy)-4-(difluoromethoxy) benzamido)pyridine 1-oxide, N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluo romethoxy-3-cyclopropyl-methoxybenzamide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Roflumilast N-oxide?

The CAS Registry Number of Roflumilast N-oxide is 292135-78-5. It is also known as 3,5-Dichloro-4-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamido)pyridine 1-oxide, 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-1-oxido-4-pyridinyl)-4-(difluoromethoxy)benzamide, N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-cyclopropylmethoxybenzamide.

What is the molecular formula and molecular weight of Roflumilast N-oxide?

Roflumilast N-oxide has the molecular formula C17H14Cl2F2N2O4 and a molecular weight of 419.2 g/mol. Its IUPAC name is 3-(cyclopropylmethoxy)-N-(3,5-dichloro-1-hydroxy-4-pyridinylidene)-4-(difluoromethoxy)benzamide.

What is Roflumilast N-oxide used for?

Roflumilast N-oxide is supplied as a characterised reference material related to Roflumilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Roflumilast N-oxide can I order?

We supply Roflumilast N-oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Roflumilast N-oxide?

Yes. Every lot of Roflumilast N-oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Roflumilast N-oxide be shipped internationally?

Yes. We export Roflumilast N-oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.