VAQORASynonyms: Tofacitinib (3S,4R)-Isomer · Epitofacitinib, (3S,4R)- · (3S,4R)-(-)-Tofacitinib isomer · Epitofacitinib, (+/-)-
(3S,4R)-Tofacitinib (CAS 1092578-48-7) – Tofacitinib reference standard. C16H20N6O, MW 312.37. Supplied by Vaqora Chemicals with COA, exported worldwide.
Listed under CAS 1092578-48-7, (3S,4R)-Tofacitinib is a high-purity reference standard of Tofacitinib available from Vaqora Chemicals. Formula C16H20N6O, molecular weight 312.37 g/mol. Systematically, it is named 3-[(3S,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile. It is also known as Tofacitinib (3S,4R)-Isomer or Epitofacitinib, (3S,4R)-.
The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.
Laboratories use this Tofacitinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.
View every impurity, metabolite and intermediate we list for Tofacitinib.
Tofacitinib impurities| Product name | (3S,4R)-Tofacitinib |
|---|---|
| Catalogue No. | VQ-028418 |
| CAS Number | 1092578-48-7 |
| IUPAC name | 3-[(3S,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile |
| Molecular formula | C16H20N6O |
| Molecular weight | 312.37 g/mol |
| Exact mass | 312.1699 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | UJLAWZDWDVHWOW-DGCLKSJQSA-N |
| SMILES | C[C@@H]1CCN(C[C@H]1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N |
| PubChem CID | 9966538 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 1.5 |
| H-bond donors / acceptors | 1 / 5 |
| TPSA | 88.9 Ų |
The CAS Registry Number of (3S,4R)-Tofacitinib is 1092578-48-7. It is also known as Tofacitinib (3S,4R)-Isomer, Epitofacitinib, (3S,4R)-, (3S,4R)-(-)-Tofacitinib isomer.
(3S,4R)-Tofacitinib has the molecular formula C16H20N6O and a molecular weight of 312.37 g/mol. Its IUPAC name is 3-[(3S,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile.
(3S,4R)-Tofacitinib is supplied as a characterised reference material related to Tofacitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
We supply (3S,4R)-Tofacitinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Yes. Every lot of (3S,4R)-Tofacitinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Yes. We export (3S,4R)-Tofacitinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
We reply within one business day with price, pack options, lead time and documentation.
![3-((3R,4R)-3-((6,7-Dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate chemical structure](/media/structures/AKIWAQYGFQGDEY-YLAFAASESA-N.svg)
![N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure](/media/structures/GWMBPMUFLFJILW-BWKNWUBXSA-N.svg)
![3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoic Acid chemical structure](/media/structures/NMGRKBVNLVHWSQ-PWSUYJOCSA-N.svg)
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