Tofacitinib N-Oxide

Name: Tofacitinib N-Oxide
Brand: Vaqora Chemicals
SKU: VQ-028415

About Tofacitinib N-Oxide

Tofacitinib N-Oxide (CAS 2028267-73-2) is a metabolite or degradation product of Tofacitinib offered by Vaqora Chemicals. Its molecular formula is C16H20N6O2 and its molecular weight is 328.37 g/mol. The IUPAC name is N-[(3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine oxide. It is also known as CP-690550N-oxide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Tofacitinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Tofacitinib N-Oxide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Tofacitinib

View every impurity, metabolite and intermediate we list for Tofacitinib.

Tofacitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Tofacitinib N-Oxide
Catalogue No.	VQ-028415
CAS Number	2028267-73-2
IUPAC name	N-[(3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine oxide
Molecular formula	C₁₆H₂₀N₆O₂
Molecular weight	328.37 g/mol
Exact mass	328.1648
Grade	Reference Standard
HSN code	38229090
InChIKey	BKXHGXXDZRQCDL-YZQUQHLXSA-N
SMILES	C[C@@H]1CCN(C[C@@H]1[N+](C)(C2=NC=NC3=C2C=CN3)[O-])C(=O)CC#N
PubChem CID	134786206

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	1 / 5
TPSA	104 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tofacitinib N-Oxide?

The CAS Registry Number of Tofacitinib N-Oxide is 2028267-73-2. It is also known as CP-690550N-oxide.

What is the molecular formula and molecular weight of Tofacitinib N-Oxide?

Tofacitinib N-Oxide has the molecular formula C16H20N6O2 and a molecular weight of 328.37 g/mol. Its IUPAC name is N-[(3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine oxide.

What is Tofacitinib N-Oxide used for?

Tofacitinib N-Oxide is supplied as a characterised reference material related to Tofacitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tofacitinib N-Oxide can I order?

We supply Tofacitinib N-Oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tofacitinib N-Oxide?

Yes. Every lot of Tofacitinib N-Oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tofacitinib N-Oxide be shipped internationally?

Yes. We export Tofacitinib N-Oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.