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VAQORACHEMICALS
API ImpuritiesReference StandardAvailable on request

4-Amino-5-aminomethyl-2-methylpyrimidine

Synonyms: Grewe Diamine · 2-Methyl-4-amino-5-aminomethylpyrimidine · 4-Amino-2-methylpyrimidine-5-methylamine · 5-Pyrimidinemethanamine, 4-amino-2-methyl-

CAS No.95-02-3
FormulaC6H10N4
Mol. weight138.17
Catalogue No.VQ-023362
PurityReference Standard
HSN38229090

4-Amino-5-aminomethyl-2-methylpyrimidine (CAS 95-02-3) – Thiamine impurity standard. C6H10N4, MW 138.17. Vaqora Chemicals: COA, global shipping.

Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
Bulk / custom pack · kg to MT
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Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing

About 4-Amino-5-aminomethyl-2-methylpyrimidine

Vaqora Chemicals supplies 4-Amino-5-aminomethyl-2-methylpyrimidine, an impurity of Thiamine registered under CAS number 95-02-3. The compound has the formula C6H10N4, corresponding to a molecular weight of 138.17 g/mol. Systematically, it is named 5-(aminomethyl)-2-methylpyrimidin-4-amine. Alternative names: Grewe Diamine and 2-Methyl-4-amino-5-aminomethylpyrimidine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Thiamine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Industries

Related to Thiamine

View every impurity, metabolite and intermediate we list for Thiamine.

Thiamine impurities

Specifications & identifiers

Chemical identifiers
Product name4-Amino-5-aminomethyl-2-methylpyrimidine
Catalogue No.VQ-023362
CAS Number95-02-3
IUPAC name5-(aminomethyl)-2-methylpyrimidin-4-amine
Molecular formulaC6H10N4
Molecular weight138.17 g/mol
Exact mass138.0905
GradeReference Standard
HSN code38229090
InChIKeyOZOHTVFCSKFMLL-UHFFFAOYSA-N
SMILESCC1=NC=C(C(=N1)N)CN
PubChem CID66762
Physical properties
Physical formSolid
LogP (XLogP3)-0.3
H-bond donors / acceptors2 / 4
TPSA77.8 Ų
SynonymsGrewe Diamine, 2-Methyl-4-amino-5-aminomethylpyrimidine, 4-Amino-2-methylpyrimidine-5-methylamine, 5-Pyrimidinemethanamine, 4-amino-2-methyl-, 4-Amino-5-Aminomethyl-2-Methylpyrimiine, 5-(Aminomethyl)-2-methyl-4-pyrimidinamine, 1-(6-imino-2-methyl-1,6-dihydropyrimidin-5-yl)methanamine, 5-(aminomethyl)-2-methylpyrimidine-4-ylamine, NChemBio.2007.13-comp17, Amino-HMP, 2-Methyl-4-amino-5-aminomethyl-pyrimidin

Safety & hazard information (GHS)

GHS05 Corrosive
Corrosive
GHS07 Harmful / irritant
Harmful / irritant

Signal word: Danger

Hazard statements

  • H315Causes skin irritation
  • H317May cause an allergic skin reaction
  • H318Causes serious eye damage
  • H319Causes serious eye irritation

Precautionary statements: P261, P264, P264 + P265, P272, P280, P302 + P352, P305 + P351 + P338, P305 + P354 + P338, P317, P321, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of 4-Amino-5-aminomethyl-2-methylpyrimidine?

The CAS Registry Number of 4-Amino-5-aminomethyl-2-methylpyrimidine is 95-02-3. It is also known as Grewe Diamine, 2-Methyl-4-amino-5-aminomethylpyrimidine, 4-Amino-2-methylpyrimidine-5-methylamine.

What is the molecular formula and molecular weight of 4-Amino-5-aminomethyl-2-methylpyrimidine?

4-Amino-5-aminomethyl-2-methylpyrimidine has the molecular formula C6H10N4 and a molecular weight of 138.17 g/mol. Its IUPAC name is 5-(aminomethyl)-2-methylpyrimidin-4-amine.

What is 4-Amino-5-aminomethyl-2-methylpyrimidine used for?

4-Amino-5-aminomethyl-2-methylpyrimidine is supplied as a characterised reference material related to Thiamine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Amino-5-aminomethyl-2-methylpyrimidine can I order?

We supply 4-Amino-5-aminomethyl-2-methylpyrimidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Amino-5-aminomethyl-2-methylpyrimidine?

Yes. Every lot of 4-Amino-5-aminomethyl-2-methylpyrimidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Amino-5-aminomethyl-2-methylpyrimidine be shipped internationally?

Yes. 4-Amino-5-aminomethyl-2-methylpyrimidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

Enquire about 4-Amino-5-aminomethyl-2-methylpyrimidine

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
How ordering works

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Reference Standard
Toxopyrimidine chemical structure
Toxopyrimidine
CAS
73-67-6
Formula
C6H9N3O
MW
139.16 g/mol
VQ-027102

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