4-Chloro-3-(trifluoromethyl)benzenesulfonyl c… 32333-53-2

Name: 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride
Brand: Vaqora Chemicals
SKU: VQ-050461

About 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride

4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride is an impurity of Sorafenib carrying the CAS registry number 32333-53-2. Its molecular formula is C7H3Cl2F3O2S and its molecular weight is 279.06 g/mol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Sorafenib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sorafenib

View every impurity, metabolite and intermediate we list for Sorafenib.

Sorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride
Catalogue No.	VQ-050461
CAS Number	32333-53-2
IUPAC name	4-chloro-3-(trifluoromethyl)benzenesulfonyl chloride
Molecular formula	C₇H₃Cl₂F₃O₂S
Molecular weight	279.06 g/mol
Exact mass	277.9183
Grade	Reference Standard
HSN code	38229090
InChIKey	SSULGNXFUGLULI-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1S(=O)(=O)Cl)C(F)(F)F)Cl
PubChem CID	2780719

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	0 / 5
TPSA	42.5 Å²
Synonyms	4-chloro-3-(trifluoromethyl)benzene-1-sulfonyl chloride, 4-chloro-3-(trifluoromethyl)benzenesulphonyl chloride, Benzenesulfonyl chloride, 4-chloro-3-(trifluoromethyl)-, 4-Chloro-3-(trifluoromethyl)phenylsulfonyl chloride, chloro[4-chloro-3-(trifluoromethyl)phenyl]sulfone, 4-chloro-3-(trifluoromethyl)benzenesulfonyl chloride, AldrichCPR

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H290May be corrosive to metals
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P234, P260, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P317, P319, P321, P330, P363, P390, P403 + P233, P405, P406, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride?

The CAS Registry Number of 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride is 32333-53-2. It is also known as 4-chloro-3-(trifluoromethyl)benzene-1-sulfonyl chloride, 4-chloro-3-(trifluoromethyl)benzenesulphonyl chloride, Benzenesulfonyl chloride, 4-chloro-3-(trifluoromethyl)-.

What is the molecular formula and molecular weight of 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride?

4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride has the molecular formula C7H3Cl2F3O2S and a molecular weight of 279.06 g/mol. Its IUPAC name is 4-chloro-3-(trifluoromethyl)benzenesulfonyl chloride.

What is 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride used for?

4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride is supplied as a characterised reference material related to Sorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride can I order?

We supply 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride?

Yes. Every lot of 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride be shipped internationally?

Yes. 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.