4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid 13721-01-2

Name: 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid
Brand: Vaqora Chemicals
SKU: VQ-031335

About 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid

Listed under CAS 13721-01-2, 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid is an impurity of Ivacaftor available from Vaqora Chemicals. Formula C10H7NO3, molecular weight 189.17 g/mol. Its systematic (IUPAC) name is 4-oxo-1H-quinoline-3-carboxylic acid. It is also known as 4-quinolone-3-carboxylic acid or 1,4-dihydro-4-oxo-3-quinolinecarboxylic acid.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Ivacaftor to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ivacaftor

View every impurity, metabolite and intermediate we list for Ivacaftor.

Ivacaftor impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid
Catalogue No.	VQ-031335
CAS Number	13721-01-2
IUPAC name	4-oxo-1H-quinoline-3-carboxylic acid
Molecular formula	C₁₀H₇NO₃
Molecular weight	189.17 g/mol
Exact mass	189.0426
Grade	Reference Standard
HSN code	38229090
InChIKey	ILNJBIQQAIIMEY-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C(=O)C(=CN2)C(=O)O
PubChem CID	220875

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	2 / 4
TPSA	66.4 Å²
Synonyms	3-Quinolinecarboxylic acid, 1,4-dihydro-4-oxo-, 4-quinolone-3-carboxylic acid, 1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 4-oxo-1,4-dihydroxy-quinoline-3-carboxylic acid, 4-Hydroxyquinoline-3-carboxylic acid, 4-Hydroxy-quinoline-3-carboxylic acid, 1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 3-Quinolinecarboxylicacid, 4-hydroxy-, 4-Hydroxy-3-quinolinecarboxylic acid, 4-Oxo-1,4-dihydroquinoline Carboxylic Acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid?

The CAS Registry Number of 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid is 13721-01-2. It is also known as 3-Quinolinecarboxylic acid, 1,4-dihydro-4-oxo-, 4-quinolone-3-carboxylic acid, 1,4-dihydro-4-oxo-3-quinolinecarboxylic acid.

What is the molecular formula and molecular weight of 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid?

4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid has the molecular formula C10H7NO3 and a molecular weight of 189.17 g/mol. Its IUPAC name is 4-oxo-1H-quinoline-3-carboxylic acid.

What is 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid used for?

4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid is supplied as a characterised reference material related to Ivacaftor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid can I order?

We supply 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid?

Yes. Every lot of 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid be shipped internationally?

Yes. 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.