De-Alkylated Ivacaftor

Name: De-Alkylated Ivacaftor
Brand: Vaqora Chemicals
SKU: VQ-031338

About De-Alkylated Ivacaftor

De-Alkylated Ivacaftor (CAS 873054-39-8) is an impurity of Ivacaftor offered by Vaqora Chemicals. Its molecular formula is C20H20N2O3 and its molecular weight is 336.4 g/mol. Systematically, it is named N-(4-tert-butyl-3-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide. Alternative names: De-tert-butyl Ivacaftor.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Ivacaftor to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ivacaftor

View every impurity, metabolite and intermediate we list for Ivacaftor.

Ivacaftor impurities

Specifications & identifiers

Chemical identifiers
Product name	De-Alkylated Ivacaftor
Catalogue No.	VQ-031338
CAS Number	873054-39-8
IUPAC name	N-(4-tert-butyl-3-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide
Molecular formula	C₂₀H₂₀N₂O₃
Molecular weight	336.4 g/mol
Exact mass	336.1474
Grade	Reference Standard
HSN code	38229090
InChIKey	RGXDSPVREBKZMQ-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=C(C=C(C=C1)NC(=O)C2=CNC3=CC=CC=C3C2=O)O
PubChem CID	57567374

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	3 / 4
TPSA	78.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of De-Alkylated Ivacaftor?

The CAS Registry Number of De-Alkylated Ivacaftor is 873054-39-8. It is also known as De-tert-butyl Ivacaftor, N-(3-hydroxy-4-tert-butyl-phenyl)-4-oxo-1H-quinoline-3-carboxamide, 3-Quinolinecarboxamide, N-[4-(1,1-dimethylethyl)-3-hydroxyphenyl]-1,4-dihydro-4-oxo-.

What is the molecular formula and molecular weight of De-Alkylated Ivacaftor?

De-Alkylated Ivacaftor has the molecular formula C20H20N2O3 and a molecular weight of 336.4 g/mol. Its IUPAC name is N-(4-tert-butyl-3-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide.

What is De-Alkylated Ivacaftor used for?

De-Alkylated Ivacaftor is supplied as a characterised reference material related to Ivacaftor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of De-Alkylated Ivacaftor can I order?

We supply De-Alkylated Ivacaftor in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with De-Alkylated Ivacaftor?

Yes. Every lot of De-Alkylated Ivacaftor is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can De-Alkylated Ivacaftor be shipped internationally?

Yes. We export De-Alkylated Ivacaftor worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.