4-Phenoxybenzoic acid

Name: 4-Phenoxybenzoic acid
Brand: Vaqora Chemicals
SKU: VQ-044699

About 4-Phenoxybenzoic acid

Listed under CAS 2215-77-2, 4-Phenoxybenzoic acid is an impurity of Ibrutinib available from Vaqora Chemicals. Its molecular formula is C13H10O3 and its molecular weight is 214.22 g/mol. Alternative names: p-Phenoxybenzoic acid and Benzoic acid, 4-phenoxy-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Ibrutinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-Phenoxybenzoic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ibrutinib

View every impurity, metabolite and intermediate we list for Ibrutinib.

Ibrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Phenoxybenzoic acid
Catalogue No.	VQ-044699
CAS Number	2215-77-2
IUPAC name	4-phenoxybenzoic acid
Molecular formula	C₁₃H₁₀O₃
Molecular weight	214.22 g/mol
Exact mass	214.063
Grade	Reference Standard
HSN code	38229090
InChIKey	RYAQFHLUEMJOMF-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)O
PubChem CID	75182

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	1 / 3
TPSA	46.5 Å²
Synonyms	p-Phenoxybenzoic acid, Benzoic acid, 4-phenoxy-, Diphenyl ether 4-carboxylic acid, 4-Carboxydiphenyl ether, Benzoic acid, p-phenoxy-, 4-Carboxybiphenyl ether, 4-carboxy biphenylether, 4CBPE, 4-PhOC6H4CO2H, p-carboxydiphenyl ether, 4-PhOC6H4COOH

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Phenoxybenzoic acid?

The CAS Registry Number of 4-Phenoxybenzoic acid is 2215-77-2. It is also known as p-Phenoxybenzoic acid, Benzoic acid, 4-phenoxy-, Diphenyl ether 4-carboxylic acid.

What is the molecular formula and molecular weight of 4-Phenoxybenzoic acid?

4-Phenoxybenzoic acid has the molecular formula C13H10O3 and a molecular weight of 214.22 g/mol. Its IUPAC name is 4-phenoxybenzoic acid.

What is 4-Phenoxybenzoic acid used for?

4-Phenoxybenzoic acid is supplied as a characterised reference material related to Ibrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Phenoxybenzoic acid can I order?

We supply 4-Phenoxybenzoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Phenoxybenzoic acid?

Yes. Every lot of 4-Phenoxybenzoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Phenoxybenzoic acid be shipped internationally?

Yes. 4-Phenoxybenzoic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.