4,5-Dimethoxy-1-indanone

Name: 4,5-Dimethoxy-1-indanone
Brand: Vaqora Chemicals
SKU: VQ-048074

About 4,5-Dimethoxy-1-indanone

Listed under CAS 6342-80-9, 4,5-Dimethoxy-1-indanone is a process intermediate or related compound of Donepezil available from Vaqora Chemicals. Formula C11H12O3, molecular weight 192.21 g/mol. Its systematic (IUPAC) name is 4,5-dimethoxy-2,3-dihydroinden-1-one. It is also known as 4,5-Dimethoxy-2,3-dihydro-1H-inden-1-one or 4,5-dimethoxyindan-1-one.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Donepezil, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4,5-Dimethoxy-1-indanone in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Donepezil

View every impurity, metabolite and intermediate we list for Donepezil.

Donepezil impurities

Specifications & identifiers

Chemical identifiers
Product name	4,5-Dimethoxy-1-indanone
Catalogue No.	VQ-048074
CAS Number	6342-80-9
IUPAC name	4,5-dimethoxy-2,3-dihydroinden-1-one
Molecular formula	C₁₁H₁₂O₃
Molecular weight	192.21 g/mol
Exact mass	192.0786
InChIKey	XQODIRIVQXQUFN-UHFFFAOYSA-N
SMILES	COC1=C(C2=C(C=C1)C(=O)CC2)OC
PubChem CID	240446

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	0 / 3
TPSA	35.5 Å²
Synonyms	4,5-Dimethoxy-2,3-dihydro-1H-inden-1-one, 4,5-dimethoxyindan-1-one, 4,5-dimethoxyindanone, 2,3-dihydro4,5-dimethoxy-1H-inden-1-one, 2,3-dihydro-4,5-dimethoxy-1H-Inden-1-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4,5-Dimethoxy-1-indanone?

The CAS Registry Number of 4,5-Dimethoxy-1-indanone is 6342-80-9. It is also known as 4,5-Dimethoxy-2,3-dihydro-1H-inden-1-one, 4,5-dimethoxyindan-1-one, 4,5-dimethoxyindanone.

What is the molecular formula and molecular weight of 4,5-Dimethoxy-1-indanone?

4,5-Dimethoxy-1-indanone has the molecular formula C11H12O3 and a molecular weight of 192.21 g/mol. Its IUPAC name is 4,5-dimethoxy-2,3-dihydroinden-1-one.

What is 4,5-Dimethoxy-1-indanone used for?

4,5-Dimethoxy-1-indanone is supplied as a characterised reference material related to Donepezil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4,5-Dimethoxy-1-indanone can I order?

We supply 4,5-Dimethoxy-1-indanone, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4,5-Dimethoxy-1-indanone?

Yes. Every lot of 4,5-Dimethoxy-1-indanone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4,5-Dimethoxy-1-indanone be shipped internationally?

Yes. 4,5-Dimethoxy-1-indanone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.