5,7-Dimethoxyindan-1-one

Name: 5,7-Dimethoxyindan-1-one
Brand: Vaqora Chemicals
SKU: VQ-048077

About 5,7-Dimethoxyindan-1-one

5,7-Dimethoxyindan-1-one is a process intermediate or related compound of Donepezil carrying the CAS registry number 880-87-5. With the molecular formula C11H12O3, it has a molar mass of 192.21 g/mol. Systematically, it is named 5,7-dimethoxy-2,3-dihydroinden-1-one. Common synonyms include 5,7-dimethoxy-1-indanone and 5,7-dimethoxy-2,3-dihydro-1H-inden-1-one.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Donepezil, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 5,7-Dimethoxyindan-1-one is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Donepezil

View every impurity, metabolite and intermediate we list for Donepezil.

Donepezil impurities

Specifications & identifiers

Chemical identifiers
Product name	5,7-Dimethoxyindan-1-one
Catalogue No.	VQ-048077
CAS Number	880-87-5
IUPAC name	5,7-dimethoxy-2,3-dihydroinden-1-one
Molecular formula	C₁₁H₁₂O₃
Molecular weight	192.21 g/mol
Exact mass	192.0786
InChIKey	ZLTCXTRHEQUDGV-UHFFFAOYSA-N
SMILES	COC1=CC2=C(C(=O)CC2)C(=C1)OC
PubChem CID	4370207

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	0 / 3
TPSA	35.5 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5,7-Dimethoxyindan-1-one?

The CAS Registry Number of 5,7-Dimethoxyindan-1-one is 880-87-5. It is also known as 5,7-dimethoxy-1-indanone, 5,7-dimethoxy-2,3-dihydro-1H-inden-1-one.

What is the molecular formula and molecular weight of 5,7-Dimethoxyindan-1-one?

5,7-Dimethoxyindan-1-one has the molecular formula C11H12O3 and a molecular weight of 192.21 g/mol. Its IUPAC name is 5,7-dimethoxy-2,3-dihydroinden-1-one.

What is 5,7-Dimethoxyindan-1-one used for?

5,7-Dimethoxyindan-1-one is supplied as a characterised reference material related to Donepezil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5,7-Dimethoxyindan-1-one can I order?

We supply 5,7-Dimethoxyindan-1-one, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5,7-Dimethoxyindan-1-one?

Yes. Every lot of 5,7-Dimethoxyindan-1-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5,7-Dimethoxyindan-1-one be shipped internationally?

Yes. 5,7-Dimethoxyindan-1-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.