Donepezil-d4 Hydrochloride

Name: Donepezil-d4 Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-048081

About Donepezil-d4 Hydrochloride

Vaqora Chemicals supplies Donepezil-d4 Hydrochloride, a stable isotope labelled analogue related to Donepezil registered under CAS number 1219798-88-5. The compound has the formula C24H30ClNO3, corresponding to a molecular weight of 420.0 g/mol. Alternative names: (+/-)-Donepezil-d4 HCl (bismethylene-d4) and TMIJ-0121.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Donepezil and related analytes in bioanalytical, pharmacokinetic and impurity studies. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Donepezil

View every impurity, metabolite and intermediate we list for Donepezil.

Donepezil impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Donepezil-d4 Hydrochloride
Catalogue No.	VQ-048081
CAS Number	1219798-88-5
IUPAC name	2-[dideuterio-[1-[dideuterio(phenyl)methyl]piperidin-4-yl]methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;hydrochloride
Molecular formula	C₂₄H₃₀ClNO₃
Molecular weight	420 g/mol
Exact mass	419.2165
Grade	Reference Standard
HSN code	38229090
InChIKey	XWAIAVWHZJNZQQ-XFRCSBOFSA-N
SMILES	[2H]C([2H])(C1CCN(CC1)C([2H])([2H])C2=CC=CC=C2)C3CC4=CC(=C(C=C4C3=O)OC)OC.Cl
PubChem CID	131869293

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 4
TPSA	38.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Donepezil-d4 Hydrochloride?

The CAS Registry Number of Donepezil-d4 Hydrochloride is 1219798-88-5. It is also known as (+/-)-Donepezil-d4 HCl (bismethylene-d4), TMIJ-0121, (+/-)-Donepezil-d4 Hydrochloride (Bismethylene-d4).

What is the molecular formula and molecular weight of Donepezil-d4 Hydrochloride?

Donepezil-d4 Hydrochloride has the molecular formula C24H30ClNO3 and a molecular weight of 420 g/mol.

What is Donepezil-d4 Hydrochloride used for?

Donepezil-d4 Hydrochloride is supplied as a characterised reference material related to Donepezil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Donepezil-d4 Hydrochloride can I order?

We supply Donepezil-d4 Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Donepezil-d4 Hydrochloride?

Yes. Every lot of Donepezil-d4 Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Donepezil-d4 Hydrochloride be shipped internationally?

Yes. We export Donepezil-d4 Hydrochloride worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.