7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[… 193686-76-9

Name: 7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Brand: Vaqora Chemicals
SKU: VQ-034347

About 7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

Vaqora Chemicals supplies 7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one, an impurity of Tolvaptan registered under CAS number 193686-76-9. Formula C17H16ClNO3S, molecular weight 349.8 g/mol. Its systematic (IUPAC) name is 7-chloro-1-(4-methylphenyl)sulfonyl-3,4-dihydro-2H-1-benzazepin-5-one.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Tolvaptan to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tolvaptan

View every impurity, metabolite and intermediate we list for Tolvaptan.

Tolvaptan impurities

Specifications & identifiers

Chemical identifiers
Product name	7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Catalogue No.	VQ-034347
CAS Number	193686-76-9
IUPAC name	7-chloro-1-(4-methylphenyl)sulfonyl-3,4-dihydro-2H-1-benzazepin-5-one
Molecular formula	C₁₇H₁₆ClNO₃S
Molecular weight	349.8 g/mol
Exact mass	349.0539
Grade	Reference Standard
HSN code	38229090
InChIKey	UMJJRQXJGYESBD-UHFFFAOYSA-N
SMILES	CC1=CC=C(C=C1)S(=O)(=O)N2CCCC(=O)C3=C2C=CC(=C3)Cl
PubChem CID	66553764

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	0 / 4
TPSA	62.8 Å²
Synonyms	7-Chloro-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-benzo[b]azepin-5-one, 7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one, 7-Chloro-1-tosyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one, 7-chloro-1-(4-methylbenzenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one, 5H-1-Benzazepin-5-one, 7-chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-, 7-chloro-1-(p-tolylsulfonyl)-3,4-dihydro-2H-1-benzazepin-5-one, 7-Chloro-1-p-toluenesulfonyl-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one, 7-chloro-5-oxo-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine, 7-chloro-5-oxo-2,3,4,5-tetrahydro-1-p-toluenesulfonyl-1H-1-benzazepine, 7-Chloro-1-(4-Mechirubenzensuruhoniru)-2,3,4,5-tetrahydro-1H-benzo [b] azepine 5-one, 7-Chloro-1-(4-methylbenzene-1-sulfonyl)-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one?

The CAS Registry Number of 7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one is 193686-76-9. It is also known as 7-Chloro-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-benzo[b]azepin-5-one, 7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one, 7-Chloro-1-tosyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one.

What is the molecular formula and molecular weight of 7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one?

7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one has the molecular formula C17H16ClNO3S and a molecular weight of 349.8 g/mol. Its IUPAC name is 7-chloro-1-(4-methylphenyl)sulfonyl-3,4-dihydro-2H-1-benzazepin-5-one.

What is 7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one used for?

7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one is supplied as a characterised reference material related to Tolvaptan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one can I order?

We supply 7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one?

Yes. Every lot of 7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one be shipped internationally?

Yes. We export 7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.