(R)-(+)-Tolvaptan

Name: (R)-(+)-Tolvaptan
Brand: Vaqora Chemicals
SKU: VQ-034350

About (R)-(+)-Tolvaptan

Listed under CAS 331947-66-1, (R)-(+)-Tolvaptan is a high-purity reference standard of Tolvaptan available from Vaqora Chemicals. With the molecular formula C26H25ClN2O3, it has a molar mass of 448.9 g/mol. Systematically, it is named N-[4-[(5R)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide. It is also known as Tolvaptan R-Isomer or Tolvaptan, (R)-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this Tolvaptan standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R)-(+)-Tolvaptan is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Tolvaptan

View every impurity, metabolite and intermediate we list for Tolvaptan.

Tolvaptan impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-(+)-Tolvaptan
Catalogue No.	VQ-034350
CAS Number	331947-66-1
IUPAC name	N-[4-[(5R)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide
Molecular formula	C₂₆H₂₅ClN₂O₃
Molecular weight	448.9 g/mol
Exact mass	448.1554
Grade	Reference Standard
HSN code	38229090
InChIKey	GYHCTFXIZSNGJT-XMMPIXPASA-N
SMILES	CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCC[C@H](C4=C3C=CC(=C4)Cl)O)C
PubChem CID	443894

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	2 / 3
TPSA	69.6 Å²
Synonyms	Tolvaptan R-Isomer, Tolvaptan, (R)-, (S)-(-)-Tolvaptan, (5R)-tolvaptan, EX-A1126

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-(+)-Tolvaptan?

The CAS Registry Number of (R)-(+)-Tolvaptan is 331947-66-1. It is also known as Tolvaptan R-Isomer, Tolvaptan, (R)-, (S)-(-)-Tolvaptan.

What is the molecular formula and molecular weight of (R)-(+)-Tolvaptan?

(R)-(+)-Tolvaptan has the molecular formula C26H25ClN2O3 and a molecular weight of 448.9 g/mol. Its IUPAC name is N-[4-[(5R)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide.

What is (R)-(+)-Tolvaptan used for?

(R)-(+)-Tolvaptan is supplied as a characterised reference material related to Tolvaptan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-(+)-Tolvaptan can I order?

We supply (R)-(+)-Tolvaptan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-(+)-Tolvaptan?

Yes. Every lot of (R)-(+)-Tolvaptan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-(+)-Tolvaptan be shipped internationally?

Yes. We export (R)-(+)-Tolvaptan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.