7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine
Synonyms: 7-Chloro-5-(2-fluorophenyl)-N-methyl-3H-1,4-benzodiazepin-2-amine · [7-Chloro-5-(2-fluoro-phenyl)-3H-benzo[e][1,4]diazepin-2-yl]-methyl-amine · N-[7-chloro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-yl]-N-methylamine
7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine (CAS 59467-61-7) – Midazolam impurity standard. C16H13ClFN3, MW 301.74. COA included.
About 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine
7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine is an impurity of Midazolam carrying the CAS registry number 59467-61-7. Formula C16H13ClFN3, molecular weight 301.74 g/mol. Its systematic (IUPAC) name is 7-chloro-5-(2-fluorophenyl)-N-methyl-1,3-dihydro-1,4-benzodiazepin-2-imine.
It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.
This Midazolam impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine is dispatched with a Certificate of Analysis (COA) to destinations worldwide. SDS and detailed specification sheets can be requested with your quotation.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Midazolam.
Midazolam impuritiesSpecifications & identifiers
| Product name | 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine |
|---|---|
| Catalogue No. | VQ-043708 |
| CAS Number | 59467-61-7 |
| IUPAC name | 7-chloro-5-(2-fluorophenyl)-N-methyl-1,3-dihydro-1,4-benzodiazepin-2-imine |
| Molecular formula | C16H13ClFN3 |
| Molecular weight | 301.74 g/mol |
| Exact mass | 301.0782 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | HXBIKXSRZGPORM-UHFFFAOYSA-N |
| SMILES | CN=C1CN=C(C2=C(N1)C=CC(=C2)Cl)C3=CC=CC=C3F |
| PubChem CID | 135721030 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 2.9 |
| H-bond donors / acceptors | 1 / 3 |
| TPSA | 36.8 Ų |
Documents
Frequently asked questions
What is the CAS number of 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine?
The CAS Registry Number of 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine is 59467-61-7. It is also known as 7-Chloro-5-(2-fluorophenyl)-N-methyl-3H-1,4-benzodiazepin-2-amine, [7-Chloro-5-(2-fluoro-phenyl)-3H-benzo[e][1,4]diazepin-2-yl]-methyl-amine, N-[7-chloro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-yl]-N-methylamine.
What is the molecular formula and molecular weight of 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine?
7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine has the molecular formula C16H13ClFN3 and a molecular weight of 301.74 g/mol. Its IUPAC name is 7-chloro-5-(2-fluorophenyl)-N-methyl-1,3-dihydro-1,4-benzodiazepin-2-imine.
What is 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine used for?
7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine is supplied as a characterised reference material related to Midazolam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine can I order?
We supply 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine?
Yes. Every lot of 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine be shipped internationally?
Yes. We export 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine
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