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7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine

Synonyms: 7-Chloro-5-(2-fluorophenyl)-N-methyl-3H-1,4-benzodiazepin-2-amine · [7-Chloro-5-(2-fluoro-phenyl)-3H-benzo[e][1,4]diazepin-2-yl]-methyl-amine · N-[7-chloro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-yl]-N-methylamine

CAS No.59467-61-7
FormulaC16H13ClFN3
Mol. weight301.74
Catalogue No.VQ-043708
PurityReference Standard
HSN38229090

7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine (CAS 59467-61-7) – Midazolam impurity standard. C16H13ClFN3, MW 301.74. COA included.

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25 mg
50 mg
100 mg
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16-section GHS SDS
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About 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine

7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine is an impurity of Midazolam carrying the CAS registry number 59467-61-7. Formula C16H13ClFN3, molecular weight 301.74 g/mol. Its systematic (IUPAC) name is 7-chloro-5-(2-fluorophenyl)-N-methyl-1,3-dihydro-1,4-benzodiazepin-2-imine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Midazolam impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine is dispatched with a Certificate of Analysis (COA) to destinations worldwide. SDS and detailed specification sheets can be requested with your quotation.

Typical applications

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Industries

Related to Midazolam

View every impurity, metabolite and intermediate we list for Midazolam.

Midazolam impurities

Specifications & identifiers

Chemical identifiers
Product name7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine
Catalogue No.VQ-043708
CAS Number59467-61-7
IUPAC name7-chloro-5-(2-fluorophenyl)-N-methyl-1,3-dihydro-1,4-benzodiazepin-2-imine
Molecular formulaC16H13ClFN3
Molecular weight301.74 g/mol
Exact mass301.0782
GradeReference Standard
HSN code38229090
InChIKeyHXBIKXSRZGPORM-UHFFFAOYSA-N
SMILESCN=C1CN=C(C2=C(N1)C=CC(=C2)Cl)C3=CC=CC=C3F
PubChem CID135721030
Physical properties
Physical formSolid
LogP (XLogP3)2.9
H-bond donors / acceptors1 / 3
TPSA36.8 Ų

Documents

Frequently asked questions

What is the CAS number of 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine?

The CAS Registry Number of 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine is 59467-61-7. It is also known as 7-Chloro-5-(2-fluorophenyl)-N-methyl-3H-1,4-benzodiazepin-2-amine, [7-Chloro-5-(2-fluoro-phenyl)-3H-benzo[e][1,4]diazepin-2-yl]-methyl-amine, N-[7-chloro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-yl]-N-methylamine.

What is the molecular formula and molecular weight of 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine?

7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine has the molecular formula C16H13ClFN3 and a molecular weight of 301.74 g/mol. Its IUPAC name is 7-chloro-5-(2-fluorophenyl)-N-methyl-1,3-dihydro-1,4-benzodiazepin-2-imine.

What is 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine used for?

7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine is supplied as a characterised reference material related to Midazolam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine can I order?

We supply 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine?

Yes. Every lot of 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine be shipped internationally?

Yes. We export 7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.

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