Acalabrutanib Intermediate 2

Name: Acalabrutanib Intermediate 2
Brand: Vaqora Chemicals
SKU: VQ-013184

About Acalabrutanib Intermediate 2

Acalabrutanib Intermediate 2 (CAS 1418307-18-2) is a process intermediate or related compound of Acalabrutinib offered by Vaqora Chemicals. Formula C18H17ClN4O2, molecular weight 356.8 g/mol. Its systematic (IUPAC) name is benzyl (2S)-2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Process chemists and analysts use it when developing synthetic routes to Acalabrutinib, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Acalabrutanib Intermediate 2 is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Acalabrutinib

View every impurity, metabolite and intermediate we list for Acalabrutinib.

Acalabrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Acalabrutanib Intermediate 2
Catalogue No.	VQ-013184
CAS Number	1418307-18-2
IUPAC name	benzyl (2S)-2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate
Molecular formula	C₁₈H₁₇ClN₄O₂
Molecular weight	356.8 g/mol
Exact mass	356.104
Grade	Reference Standard
HSN code	2933
InChIKey	CVBYUIZTUMXADS-AWEZNQCLSA-N
SMILES	C1C[C@H](N(C1)C(=O)OCC2=CC=CC=C2)C3=NC=C4N3C=CN=C4Cl
PubChem CID	86720301

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	0 / 4
TPSA	59.7 Å²
Synonyms	Benzyl (2S)-2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)-1-pyrrolidinecarboxylate, (S)-Benzyl 2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate, benzyl (2S)-2-{8-chloroimidazo[1,5-a]pyrazin-3-yl}pyrrolidine-1-carboxylate, (S)-Benzyl-2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate, (S)-3-(1-Cbz-pyrrolidin-2-yl)-8-chloroimidazo[1,5-a]pyrazine, Benzyl 2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate, (S)-, Phenylmethyl (2S)-2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)-1-pyrrolidinecarboxylate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Acalabrutanib Intermediate 2?

The CAS Registry Number of Acalabrutanib Intermediate 2 is 1418307-18-2. It is also known as Benzyl (2S)-2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)-1-pyrrolidinecarboxylate, (S)-Benzyl 2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate, benzyl (2S)-2-{8-chloroimidazo[1,5-a]pyrazin-3-yl}pyrrolidine-1-carboxylate.

What is the molecular formula and molecular weight of Acalabrutanib Intermediate 2?

Acalabrutanib Intermediate 2 has the molecular formula C18H17ClN4O2 and a molecular weight of 356.8 g/mol. Its IUPAC name is benzyl (2S)-2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate.

What is Acalabrutanib Intermediate 2 used for?

Acalabrutanib Intermediate 2 is supplied as a characterised reference material related to Acalabrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Acalabrutanib Intermediate 2 can I order?

We supply Acalabrutanib Intermediate 2 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Acalabrutanib Intermediate 2?

Yes. Every lot of Acalabrutanib Intermediate 2 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Acalabrutanib Intermediate 2 be shipped internationally?

Yes. We export Acalabrutanib Intermediate 2 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.