Afatinib Nitroquinazolinol Impurity

Name: Afatinib Nitroquinazolinol Impurity
Brand: Vaqora Chemicals
SKU: VQ-021444

About Afatinib Nitroquinazolinol Impurity

Afatinib Nitroquinazolinol Impurity is an impurity of Afatinib carrying the CAS registry number 1449430-45-8. The compound has the formula C14H8ClFN4O3, corresponding to a molecular weight of 334.69 g/mol. The IUPAC name is 4-(3-chloro-4-fluoroanilino)-6-nitroquinazolin-7-ol.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

This Afatinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Afatinib Nitroquinazolinol Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Afatinib

View every impurity, metabolite and intermediate we list for Afatinib.

Afatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Afatinib Nitroquinazolinol Impurity
Catalogue No.	VQ-021444
CAS Number	1449430-45-8
IUPAC name	4-(3-chloro-4-fluoroanilino)-6-nitroquinazolin-7-ol
Molecular formula	C₁₄H₈ClFN₄O₃
Molecular weight	334.69 g/mol
Exact mass	334.0269
Grade	Reference Standard
HSN code	38229090
InChIKey	ODEICIIOTUWISY-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1NC2=NC=NC3=CC(=C(C=C32)[N+](=O)[O-])O)Cl)F
PubChem CID	137285542

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	2 / 7
TPSA	104 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Afatinib Nitroquinazolinol Impurity?

The CAS Registry Number of Afatinib Nitroquinazolinol Impurity is 1449430-45-8. It is also known as 4-((3-Chloro-4-fluorophenyl)amino)-6-nitroquinazolin-7-ol, 4-[(3-chloro-4-fluorophenyl)amino]-6-nitroquinazolin-7-ol, 7-Quinazolinol, 4-[(3-chloro-4-fluorophenyl)amino]-6-nitro-.

What is the molecular formula and molecular weight of Afatinib Nitroquinazolinol Impurity?

Afatinib Nitroquinazolinol Impurity has the molecular formula C14H8ClFN4O3 and a molecular weight of 334.69 g/mol. Its IUPAC name is 4-(3-chloro-4-fluoroanilino)-6-nitroquinazolin-7-ol.

What is Afatinib Nitroquinazolinol Impurity used for?

Afatinib Nitroquinazolinol Impurity is supplied as a characterised reference material related to Afatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Afatinib Nitroquinazolinol Impurity can I order?

We supply Afatinib Nitroquinazolinol Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Afatinib Nitroquinazolinol Impurity?

Yes. Every lot of Afatinib Nitroquinazolinol Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Afatinib Nitroquinazolinol Impurity be shipped internationally?

Yes. We export Afatinib Nitroquinazolinol Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.