Ambrisentan Methyl Ester

Name: Ambrisentan Methyl Ester
Brand: Vaqora Chemicals
SKU: VQ-020781

About Ambrisentan Methyl Ester

Ambrisentan Methyl Ester (CAS 1106685-61-3) is an impurity of Ambrisentan offered by Vaqora Chemicals. Formula C23H24N2O4, molecular weight 392.4 g/mol. The IUPAC name is methyl (2S)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Ambrisentan, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ambrisentan Methyl Ester in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ambrisentan

View every impurity, metabolite and intermediate we list for Ambrisentan.

Ambrisentan impurities

Specifications & identifiers

Chemical identifiers
Product name	Ambrisentan Methyl Ester
Catalogue No.	VQ-020781
CAS Number	1106685-61-3
IUPAC name	methyl (2S)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoate
Molecular formula	C₂₃H₂₄N₂O₄
Molecular weight	392.4 g/mol
Exact mass	392.1736
Grade	Reference Standard
HSN code	38229090
InChIKey	RCOLWOXJIUGEGI-HXUWFJFHSA-N
SMILES	CC1=CC(=NC(=N1)O[C@H](C(=O)OC)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)C
PubChem CID	46244104

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	0 / 6
TPSA	70.5 Å²
Synonyms	(S)-Methyl 2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoate, (S)-Methyl 2-((4,6-dimethylpyrimidin-2-yl)-oxy)-3-methoxy-3,3-diphenylpropanoate, (s)-methyl 2-(4,6-dimethylpyrimidin-2-yloxy)-3-methoxy-3,3-diphenylpropanoate, (S)-Methyl2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoate, methyl (2S)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenyl-propanoate, Methyl (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ambrisentan Methyl Ester?

The CAS Registry Number of Ambrisentan Methyl Ester is 1106685-61-3. It is also known as (S)-Methyl 2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoate, (S)-Methyl 2-((4,6-dimethylpyrimidin-2-yl)-oxy)-3-methoxy-3,3-diphenylpropanoate, (s)-methyl 2-(4,6-dimethylpyrimidin-2-yloxy)-3-methoxy-3,3-diphenylpropanoate.

What is the molecular formula and molecular weight of Ambrisentan Methyl Ester?

Ambrisentan Methyl Ester has the molecular formula C23H24N2O4 and a molecular weight of 392.4 g/mol. Its IUPAC name is methyl (2S)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoate.

What is Ambrisentan Methyl Ester used for?

Ambrisentan Methyl Ester is supplied as a characterised reference material related to Ambrisentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ambrisentan Methyl Ester can I order?

We supply Ambrisentan Methyl Ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ambrisentan Methyl Ester?

Yes. Every lot of Ambrisentan Methyl Ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ambrisentan Methyl Ester be shipped internationally?

Yes. We export Ambrisentan Methyl Ester worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.