Amitriptyline-d6 Hydrochloride

Name: Amitriptyline-d6 Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-024250

About Amitriptyline-d6 Hydrochloride

Amitriptyline-d6 Hydrochloride is a stable isotope labelled analogue related to Amitriptyline carrying the CAS registry number 203645-63-0. With the molecular formula C20H24ClN, it has a molar mass of 319.9 g/mol. Common synonyms include Amitriptyline-d6 HCl and Amitriptyline-d6 HCl (N,N-dimethyl-d6).

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Amitriptyline-d6 Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Amitriptyline

View every impurity, metabolite and intermediate we list for Amitriptyline.

Amitriptyline impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Amitriptyline-d6 Hydrochloride
Catalogue No.	VQ-024250
CAS Number	203645-63-0
IUPAC name	3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)-N,N-bis(trideuteriomethyl)propan-1-amine;hydrochloride
Molecular formula	C₂₀H₂₄ClN
Molecular weight	319.9 g/mol
Exact mass	319.1974
Grade	Reference Standard
HSN code	38229090
InChIKey	KFYRPLNVJVHZGT-TXHXQZCNSA-N
SMILES	[2H]C([2H])([2H])N(CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31)C([2H])([2H])[2H].Cl
PubChem CID	76974221

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 1
TPSA	3.2 Å²

Safety & hazard information (GHS)

Toxic

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H319Causes serious eye irritation
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P264, P264 + P265, P270, P273, P280, P301 + P316, P305 + P351 + P338, P321, P330, P337 + P317, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Amitriptyline-d6 Hydrochloride?

The CAS Registry Number of Amitriptyline-d6 Hydrochloride is 203645-63-0. It is also known as Amitriptyline-d6 HCl, Amitriptyline-d6 HCl (N,N-dimethyl-d6), TMID-0187.

What is the molecular formula and molecular weight of Amitriptyline-d6 Hydrochloride?

Amitriptyline-d6 Hydrochloride has the molecular formula C20H24ClN and a molecular weight of 319.9 g/mol.

What is Amitriptyline-d6 Hydrochloride used for?

Amitriptyline-d6 Hydrochloride is supplied as a characterised reference material related to Amitriptyline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Amitriptyline-d6 Hydrochloride can I order?

We supply Amitriptyline-d6 Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Amitriptyline-d6 Hydrochloride?

Yes. Every lot of Amitriptyline-d6 Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Amitriptyline-d6 Hydrochloride be shipped internationally?

Yes. Amitriptyline-d6 Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.