Amitriptyline EP Impurity D

Name: Amitriptyline EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-021557

About Amitriptyline EP Impurity D

Listed under CAS 1159-03-1, Amitriptyline EP Impurity D is a pharmacopeial impurity of Amitriptyline available from Vaqora Chemicals. With the molecular formula C20H25NO, it has a molar mass of 295.4 g/mol. Systematically, it is named 2-[3-(dimethylamino)propyl]tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-2-ol. Alternative names: Amitriptyline hydrochloride EP Impurity D and Nortriptyline EP Impurity D.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Amitriptyline, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Amitriptyline EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Amitriptyline

View every impurity, metabolite and intermediate we list for Amitriptyline.

Amitriptyline impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Amitriptyline EP Impurity D
Catalogue No.	VQ-021557
CAS Number	1159-03-1
IUPAC name	2-[3-(dimethylamino)propyl]tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-2-ol
Molecular formula	C₂₀H₂₅NO
Molecular weight	295.4 g/mol
Exact mass	295.1936
Grade	Reference Standard
HSN code	38229090
InChIKey	ONSQUXZPOPTSQF-UHFFFAOYSA-N
SMILES	CN(C)CCCC1(C2=CC=CC=C2CCC3=CC=CC=C31)O
PubChem CID	14390

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	1 / 2
TPSA	23.5 Å²
Synonyms	Amitriptyline hydrochloride EP Impurity D, Nortriptyline EP Impurity D, Amitriptyline EP Impurity D, amitriptyline USP rc b, Amitriptyline Hydrochloride - Impurity D, Nortriptyline Hydrochloride - Impurity D, Amitriptynol, 5-(3-(Dimethylamino)propyl)-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ol, 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ol, 5-(3-Dimethylaminopropyl)5-dibenzo(a,d)cycloheptadienol, 5-(3-Dimethylaminopropyl)-10,11-dihydrodibenzo[a,d]cyclohepten-5-ol, 10,11-Dihydro-5-(3-dimethylaminopropyl)-5H-dibenzo(a,d)cyclohepten-5-ol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P305 + P351 + P338, P330, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Amitriptyline EP Impurity D?

The CAS Registry Number of Amitriptyline EP Impurity D is 1159-03-1. It is also known as Amitriptyline hydrochloride EP Impurity D, Nortriptyline EP Impurity D, Amitriptyline EP Impurity D.

What is the molecular formula and molecular weight of Amitriptyline EP Impurity D?

Amitriptyline EP Impurity D has the molecular formula C20H25NO and a molecular weight of 295.4 g/mol. Its IUPAC name is 2-[3-(dimethylamino)propyl]tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-2-ol.

What is Amitriptyline EP Impurity D used for?

Amitriptyline EP Impurity D is supplied as a characterised reference material related to Amitriptyline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Amitriptyline EP Impurity D can I order?

We supply Amitriptyline EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Amitriptyline EP Impurity D?

Yes. Every lot of Amitriptyline EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Amitriptyline EP Impurity D be shipped internationally?

Yes. Amitriptyline EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.