Amlodipine EP Impurity C (Stage-1, Methyl)

Name: Amlodipine EP Impurity C (Stage-1, Methyl)
Brand: Vaqora Chemicals
SKU: VQ-006228

About Amlodipine EP Impurity C (Stage-1, Methyl)

Vaqora Chemicals supplies Amlodipine EP Impurity C (Stage-1, Methyl), a pharmacopeial impurity of Amlodipine registered under CAS number 111429-90-4 at a purity of 91%. The compound has the formula C15H15NO6, corresponding to a molecular weight of 305.28 g/mol. The IUPAC name is methyl 4-[2-(1,3-dioxoisoindol-2-yl)ethoxy]-3-oxobutanoate. Common synonyms include Methyl 4-[2-(phthalimido)-ethoxy]acetoacetate and Amlodipine Impurity N2.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Amlodipine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Amlodipine EP Impurity C (Stage-1, Methyl) is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Amlodipine

View every impurity, metabolite and intermediate we list for Amlodipine.

Amlodipine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Amlodipine EP Impurity C (Stage-1, Methyl)
Catalogue No.	VQ-006228
CAS Number	111429-90-4
IUPAC name	methyl 4-[2-(1,3-dioxoisoindol-2-yl)ethoxy]-3-oxobutanoate
Molecular formula	C₁₅H₁₅NO₆
Molecular weight	305.28 g/mol
Exact mass	305.0899
Grade	Reference Standard
Purity / assay	91%
HSN code	38229090
InChIKey	REMRSOODVLLZCK-UHFFFAOYSA-N
SMILES	COC(=O)CC(=O)COCCN1C(=O)C2=CC=CC=C2C1=O
PubChem CID	22568398

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	0 / 6
TPSA	90 Å²
Synonyms	4-[2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Methyl Ester, 4-[2-(1,3-Dioxo-1,3-dihydroisoindol-2-yl)ethoxy]-3-oxobutyric acid methyl ester, Methyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate, Methyl 4-[2-(phthalimido)-ethoxy]acetoacetate, methyl 4-[2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)ethoxy]-3-oxobutanoate, Amlodipine Impurity N2, methyl 4-(2-(phthalimido)ethoxy)acetoacetate, Methyl4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate, methyl 4-[2-(1,3-dioxoisoindolin-2-yl)ethoxy]-3-oxo-butanoate, 4-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethoxy]-3-oxo-butyric acid methyl ester, 4-[2-(1,3-Dioxo-1,3-dihydroisoindol-2-yl)-ethoxy]-3-oxo-butyric acid methyl ester

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Amlodipine EP Impurity C (Stage-1, Methyl)?

The CAS Registry Number of Amlodipine EP Impurity C (Stage-1, Methyl) is 111429-90-4. It is also known as 4-[2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Methyl Ester, 4-[2-(1,3-Dioxo-1,3-dihydroisoindol-2-yl)ethoxy]-3-oxobutyric acid methyl ester, Methyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate.

What is the molecular formula and molecular weight of Amlodipine EP Impurity C (Stage-1, Methyl)?

Amlodipine EP Impurity C (Stage-1, Methyl) has the molecular formula C15H15NO6 and a molecular weight of 305.28 g/mol. Its IUPAC name is methyl 4-[2-(1,3-dioxoisoindol-2-yl)ethoxy]-3-oxobutanoate.

What is Amlodipine EP Impurity C (Stage-1, Methyl) used for?

Amlodipine EP Impurity C (Stage-1, Methyl) is supplied as a characterised reference material related to Amlodipine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Amlodipine EP Impurity C (Stage-1, Methyl) can I order?

We supply Amlodipine EP Impurity C (Stage-1, Methyl) in Reference Standard (91%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Amlodipine EP Impurity C (Stage-1, Methyl)?

Yes. Every lot of Amlodipine EP Impurity C (Stage-1, Methyl) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Amlodipine EP Impurity C (Stage-1, Methyl) be shipped internationally?

Yes. We export Amlodipine EP Impurity C (Stage-1, Methyl) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.