Amlodipine EP Impurity E

Name: Amlodipine EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-006232

About Amlodipine EP Impurity E

Vaqora Chemicals supplies Amlodipine EP Impurity E, a pharmacopeial impurity of Amlodipine registered under CAS number 140171-65-9, specified at 92.99% purity. The compound has the formula C21H27ClN2O5, corresponding to a molecular weight of 422.9 g/mol. Its systematic (IUPAC) name is diethyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate. Alternative names: Amlodipine Diethyl Ester and Amlodipine USP Related Compound E.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Amlodipine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Amlodipine EP Impurity E is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Amlodipine

View every impurity, metabolite and intermediate we list for Amlodipine.

Amlodipine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Amlodipine EP Impurity E
Catalogue No.	VQ-006232
CAS Number	140171-65-9
IUPAC name	diethyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Molecular formula	C₂₁H₂₇ClN₂O₅
Molecular weight	422.9 g/mol
Exact mass	422.1608
Grade	Reference Standard
Purity / assay	92.99%
HSN code	38229090
InChIKey	BGGLOZPVAWMSEB-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OCC)COCCN)C
PubChem CID	11293140

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	2 / 7
TPSA	99.9 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Amlodipine EP Impurity E?

The CAS Registry Number of Amlodipine EP Impurity E is 140171-65-9. It is also known as Amlodipine Diethyl Ester, Amlodipine USP Related Compound E, Amlodipine besilate impurity E.

What is the molecular formula and molecular weight of Amlodipine EP Impurity E?

Amlodipine EP Impurity E has the molecular formula C21H27ClN2O5 and a molecular weight of 422.9 g/mol. Its IUPAC name is diethyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate.

What is Amlodipine EP Impurity E used for?

Amlodipine EP Impurity E is supplied as a characterised reference material related to Amlodipine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Amlodipine EP Impurity E can I order?

We supply Amlodipine EP Impurity E in Reference Standard (92.99%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Amlodipine EP Impurity E?

Yes. Every lot of Amlodipine EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Amlodipine EP Impurity E be shipped internationally?

Yes. Amlodipine EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.