Anastrozole EP Impurity H
Synonyms: 3,5-Bis(2-cyano-2-methylethyl)toluene · 3,5-Bis(2-cyanoprop-2-yl)toluene · α1,α1,α3,α3,5-Pentamethyl-1,3-benzenediacetonitrile · 2-[3-(Cyanodimethylmethyl)-5-methylphenyl]-2-methylpropionitrile
Anastrozole EP Impurity H (CAS 120511-72-0) – Anastrozole impurity standard. C15H18N2, MW 226.32. Order from Vaqora Chemicals with COA and global delivery.
About Anastrozole EP Impurity H
Listed under CAS 120511-72-0, Anastrozole EP Impurity H is a pharmacopeial impurity of Anastrozole available from Vaqora Chemicals. Formula C15H18N2, molecular weight 226.32 g/mol. The IUPAC name is 2-[3-(2-cyanopropan-2-yl)-5-methylphenyl]-2-methylpropanenitrile. Alternative names: 3,5-Bis(2-cyano-2-methylethyl)toluene and 3,5-Bis(2-cyanoprop-2-yl)toluene.
The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 6 hazard statements. Review the Safety Data Sheet before use.
Pharmaceutical QC and development laboratories use this impurity standard of Anastrozole to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.
Typical applications
- Pharmacopeial method verification
- Impurity profiling
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Anastrozole.
Anastrozole impuritiesGrade guides
Specifications & identifiers
| Product name | Anastrozole EP Impurity H |
|---|---|
| Catalogue No. | VQ-006242 |
| CAS Number | 120511-72-0 |
| IUPAC name | 2-[3-(2-cyanopropan-2-yl)-5-methylphenyl]-2-methylpropanenitrile |
| Molecular formula | C15H18N2 |
| Molecular weight | 226.32 g/mol |
| Exact mass | 226.147 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | SJECEXNMZXMXNE-UHFFFAOYSA-N |
| SMILES | CC1=CC(=CC(=C1)C(C)(C)C#N)C(C)(C)C#N |
| PubChem CID | 16005484 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 3.5 |
| H-bond donors / acceptors | 0 / 2 |
| TPSA | 47.6 Ų |
| Synonyms | 3,5-Bis(2-cyano-2-methylethyl)toluene, 3,5-Bis(2-cyanoprop-2-yl)toluene, α1,α1,α3,α3,5-Pentamethyl-1,3-benzenediacetonitrile, 2-[3-(Cyanodimethylmethyl)-5-methylphenyl]-2-methylpropionitrile, 2,2′-(5-Methyl-1,3-phenylene)bis(2-methylpropanenitrile), 2,2'-(5-Methyl-1,3-phenylene)bis(2-methylpropanenitrile), Anastrozole Related Compound A, 2,2'-(5-Methyl-1,3-phenylene)di(2-methylpropionitrile), 1,3-Benzenediacetonitrile, alpha1,alpha1,alpha3,alpha3,5-pentamethyl-, Anastrozole impurity H, 2,2'-(5-methyl-1,3-phenylene)-di-(2-methylpropionitrile), 2,2'-(5-Methyl-1,3-phenylene)di(2-methylpropiononitrile) |
Safety & hazard information (GHS)
Signal word: Danger
Hazard statements
H302Harmful if swallowedH315Causes skin irritationH319Causes serious eye irritationH335May cause respiratory irritationH360May damage fertility or the unborn childH413May cause long lasting harmful effects to aquatic life
Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Anastrozole EP Impurity H?
The CAS Registry Number of Anastrozole EP Impurity H is 120511-72-0. It is also known as 3,5-Bis(2-cyano-2-methylethyl)toluene, 3,5-Bis(2-cyanoprop-2-yl)toluene, α1,α1,α3,α3,5-Pentamethyl-1,3-benzenediacetonitrile.
What is the molecular formula and molecular weight of Anastrozole EP Impurity H?
Anastrozole EP Impurity H has the molecular formula C15H18N2 and a molecular weight of 226.32 g/mol. Its IUPAC name is 2-[3-(2-cyanopropan-2-yl)-5-methylphenyl]-2-methylpropanenitrile.
What is Anastrozole EP Impurity H used for?
Anastrozole EP Impurity H is supplied as a characterised reference material related to Anastrozole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Anastrozole EP Impurity H can I order?
We supply Anastrozole EP Impurity H in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Anastrozole EP Impurity H?
Yes. Every lot of Anastrozole EP Impurity H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Anastrozole EP Impurity H be shipped internationally?
Yes. Anastrozole EP Impurity H is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Anastrozole EP Impurity H
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