Aprepitant N-Oxide

Name: Aprepitant N-Oxide
Brand: Vaqora Chemicals
SKU: VQ-024347

About Aprepitant N-Oxide

Aprepitant N-Oxide (CAS 172673-23-3) is a metabolite or degradation product of Aprepitant offered by Vaqora Chemicals. With the molecular formula C23H21F7N4O4, it has a molar mass of 550.4 g/mol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Aprepitant, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Aprepitant N-Oxide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Aprepitant

View every impurity, metabolite and intermediate we list for Aprepitant.

Aprepitant impurities

Specifications & identifiers

Chemical identifiers
Product name	Aprepitant N-Oxide
Catalogue No.	VQ-024347
CAS Number	172673-23-3
IUPAC name	3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-oxidomorpholin-4-ium-4-yl]methyl]-1,4-dihydro-1,2,4-triazol-5-one
Molecular formula	C₂₃H₂₁F₇N₄O₄
Molecular weight	550.4 g/mol
Exact mass	550.1451
Grade	Reference Standard
HSN code	38229090
InChIKey	CXAQOLFUIZCJSQ-FMSQANQXSA-N
SMILES	C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H]([N+](CCO2)(CC3=NNC(=O)N3)[O-])C4=CC=C(C=C4)F
PubChem CID	137184357

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	2 / 12
TPSA	90 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Aprepitant N-Oxide?

The CAS Registry Number of Aprepitant N-Oxide is 172673-23-3.

What is the molecular formula and molecular weight of Aprepitant N-Oxide?

Aprepitant N-Oxide has the molecular formula C23H21F7N4O4 and a molecular weight of 550.4 g/mol. Its IUPAC name is 3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-oxidomorpholin-4-ium-4-yl]methyl]-1,4-dihydro-1,2,4-triazol-5-one.

What is Aprepitant N-Oxide used for?

Aprepitant N-Oxide is supplied as a characterised reference material related to Aprepitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Aprepitant N-Oxide can I order?

We supply Aprepitant N-Oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Aprepitant N-Oxide?

Yes. Every lot of Aprepitant N-Oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Aprepitant N-Oxide be shipped internationally?

Yes. We export Aprepitant N-Oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.