N-(Destriazolonomethyl) N-(Methylcarboxyaceta… 219821-37-1

Name: N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant
Brand: Vaqora Chemicals
SKU: VQ-024346

About N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant

N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant (CAS 219821-37-1) is a metabolite or degradation product of Aprepitant offered by Vaqora Chemicals. Its molecular formula is C24H25F7N4O4 and its molecular weight is 566.5 g/mol. Alternative names: Aprepitant open ring methyl ester.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Aprepitant, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Aprepitant

View every impurity, metabolite and intermediate we list for Aprepitant.

Aprepitant impurities

Specifications & identifiers

Chemical identifiers
Product name	N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant
Catalogue No.	VQ-024346
CAS Number	219821-37-1
IUPAC name	methyl N-[(Z)-[1-amino-2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]ethylidene]amino]carbamate
Molecular formula	C₂₄H₂₅F₇N₄O₄
Molecular weight	566.5 g/mol
Exact mass	566.1764
Grade	Reference Standard
HSN code	38229090
InChIKey	JMBSYJOVXPFTFD-HBUDHLSFSA-N
SMILES	C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)C/C(=N/NC(=O)OC)/N)C3=CC=C(C=C3)F
PubChem CID	11261570

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	2 / 13
TPSA	98.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant?

The CAS Registry Number of N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant is 219821-37-1. It is also known as Aprepitant open ring methyl ester.

What is the molecular formula and molecular weight of N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant?

N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant has the molecular formula C24H25F7N4O4 and a molecular weight of 566.5 g/mol. Its IUPAC name is methyl N-[(Z)-[1-amino-2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]ethylidene]amino]carbamate.

What is N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant used for?

N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant is supplied as a characterised reference material related to Aprepitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant can I order?

We supply N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant?

Yes. Every lot of N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant be shipped internationally?

Yes. We export N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.