Avapritinib

Name: Avapritinib
Brand: Vaqora Chemicals
SKU: VQ-024438

About Avapritinib

Listed under CAS 1703793-34-3, Avapritinib is a high-purity reference standard of Avapritinib available from Vaqora Chemicals. The compound has the formula C26H27FN10, corresponding to a molecular weight of 498.6 g/mol. It is also known as Avapritinib (WSM) or BLU-285.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this Avapritinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Avapritinib is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Avapritinib

View every impurity, metabolite and intermediate we list for Avapritinib.

Avapritinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Avapritinib
Catalogue No.	VQ-024438
CAS Number	1703793-34-3
IUPAC name	(1S)-1-(4-fluorophenyl)-1-[2-[4-[6-(1-methylpyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl]pyrimidin-5-yl]ethanamine
Molecular formula	C₂₆H₂₇FN₁₀
Molecular weight	498.6 g/mol
Exact mass	498.2404
Grade	Reference Standard
HSN code	38229090
InChIKey	DWYRIWUZIJHQKQ-SANMLTNESA-N
SMILES	C[C@](C1=CC=C(C=C1)F)(C2=CN=C(N=C2)N3CCN(CC3)C4=NC=NN5C4=CC(=C5)C6=CN(N=C6)C)N
PubChem CID	118023034

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	1 / 9
TPSA	106 Å²
Synonyms	Avapritinib (WSM), BLU-285, PDGFR alpha/KIT Mutant-specific Inhibitor BLU-285, BLU-285 (Avapritinib), US10807985, Compound 44, Avapritinib (BLU-285), 9JI, BLU 285, EX-A1366

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Avapritinib?

The CAS Registry Number of Avapritinib is 1703793-34-3. It is also known as Avapritinib (WSM), BLU-285, PDGFR alpha/KIT Mutant-specific Inhibitor BLU-285.

What is the molecular formula and molecular weight of Avapritinib?

Avapritinib has the molecular formula C26H27FN10 and a molecular weight of 498.6 g/mol. Its IUPAC name is (1S)-1-(4-fluorophenyl)-1-[2-[4-[6-(1-methylpyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl]pyrimidin-5-yl]ethanamine.

What is Avapritinib used for?

Avapritinib is supplied as a characterised reference material related to Avapritinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Avapritinib can I order?

We supply Avapritinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Avapritinib?

Yes. Every lot of Avapritinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Avapritinib be shipped internationally?

Yes. We export Avapritinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.