R-Avapritinib

Name: R-Avapritinib
Brand: Vaqora Chemicals
SKU: VQ-047490

About R-Avapritinib

R-Avapritinib (CAS 1703793-32-1) is an impurity of Avapritinib offered by Vaqora Chemicals. Its molecular formula is C26H27FN10 and its molecular weight is 498.6 g/mol. Common synonyms include US10807985, Compound 43.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Avapritinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, R-Avapritinib is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Avapritinib

View every impurity, metabolite and intermediate we list for Avapritinib.

Avapritinib impurities

Specifications & identifiers

Chemical identifiers
Product name	R-Avapritinib
Catalogue No.	VQ-047490
CAS Number	1703793-32-1
IUPAC name	(1R)-1-(4-fluorophenyl)-1-[2-[4-[6-(1-methylpyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl]pyrimidin-5-yl]ethanamine
Molecular formula	C₂₆H₂₇FN₁₀
Molecular weight	498.6 g/mol
Exact mass	498.2404
Grade	Reference Standard
HSN code	38229090
InChIKey	DWYRIWUZIJHQKQ-AREMUKBSSA-N
SMILES	C[C@@](C1=CC=C(C=C1)F)(C2=CN=C(N=C2)N3CCN(CC3)C4=NC=NN5C4=CC(=C5)C6=CN(N=C6)C)N
PubChem CID	118023534

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	1 / 9
TPSA	106 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of R-Avapritinib?

The CAS Registry Number of R-Avapritinib is 1703793-32-1. It is also known as US10807985, Compound 43.

What is the molecular formula and molecular weight of R-Avapritinib?

R-Avapritinib has the molecular formula C26H27FN10 and a molecular weight of 498.6 g/mol. Its IUPAC name is (1R)-1-(4-fluorophenyl)-1-[2-[4-[6-(1-methylpyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl]pyrimidin-5-yl]ethanamine.

What is R-Avapritinib used for?

R-Avapritinib is supplied as a characterised reference material related to Avapritinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of R-Avapritinib can I order?

We supply R-Avapritinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with R-Avapritinib?

Yes. Every lot of R-Avapritinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can R-Avapritinib be shipped internationally?

Yes. We export R-Avapritinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.