Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxyla… 1208361-39-0

Name: Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate
Brand: Vaqora Chemicals
SKU: VQ-035866

About Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate

Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate is an impurity of Avapritinib carrying the CAS registry number 1208361-39-0. The compound has the formula C6H7BrN2O2, corresponding to a molecular weight of 219.04 g/mol. The IUPAC name is methyl 1-amino-4-bromopyrrole-2-carboxylate. It is also known as methyl1-amino-4-bromo-pyrrole-2-carboxylate or methyl 1-amino-4-bromo-pyrrole-2-carboxylate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Avapritinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Avapritinib

View every impurity, metabolite and intermediate we list for Avapritinib.

Avapritinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate
Catalogue No.	VQ-035866
CAS Number	1208361-39-0
IUPAC name	methyl 1-amino-4-bromopyrrole-2-carboxylate
Molecular formula	C₆H₇BrN₂O₂
Molecular weight	219.04 g/mol
Exact mass	217.9691
Grade	Reference Standard
HSN code	38229090
InChIKey	ACXDDRPCBGQPBV-UHFFFAOYSA-N
SMILES	COC(=O)C1=CC(=CN1N)Br
PubChem CID	58423493

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	1 / 3
TPSA	57.3 Å²
Synonyms	1-amino-4-bromo-1H-pyrrole-2-carboxylic acid methyl ester, methyl 4-bromo-1-aminopyrrole-2-carboxylate hydrochloride, methyl1-amino-4-bromo-pyrrole-2-carboxylate, methyl 1-amino-4-bromo-pyrrole-2-carboxylate, 1H-Pyrrole-2-carboxylic acid, 1-amino-4-bromo-, methyl ester

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate?

The CAS Registry Number of Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate is 1208361-39-0. It is also known as 1-amino-4-bromo-1H-pyrrole-2-carboxylic acid methyl ester, methyl 4-bromo-1-aminopyrrole-2-carboxylate hydrochloride, methyl1-amino-4-bromo-pyrrole-2-carboxylate.

What is the molecular formula and molecular weight of Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate?

Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate has the molecular formula C6H7BrN2O2 and a molecular weight of 219.04 g/mol. Its IUPAC name is methyl 1-amino-4-bromopyrrole-2-carboxylate.

What is Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate used for?

Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate is supplied as a characterised reference material related to Avapritinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate can I order?

We supply Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate?

Yes. Every lot of Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate be shipped internationally?

Yes. Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.