Biotin-d2

Name: Biotin-d2
Brand: Vaqora Chemicals
SKU: VQ-044255

About Biotin-d2

Listed under CAS 1217481-41-8, Biotin-d2 is a stable isotope labelled analogue related to Biotin available from Vaqora Chemicals. The compound has the formula C10H16N2O3S, corresponding to a molecular weight of 246.33 g/mol. Its systematic (IUPAC) name is 5-[(3aR,6S,6aS)-4,4-dideuterio-2-oxo-3,3a,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]pentanoic acid. It is also known as Biotin-d2-1 or Biotin-[D2] (Vitamin H-[D2]).

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Biotin-d2 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Biotin

View every impurity, metabolite and intermediate we list for Biotin.

Biotin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Biotin-d2
Catalogue No.	VQ-044255
CAS Number	1217481-41-8
IUPAC name	5-[(3aR,6S,6aS)-4,4-dideuterio-2-oxo-3,3a,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]pentanoic acid
Molecular formula	C₁₀H₁₆N₂O₃S
Molecular weight	246.33 g/mol
Exact mass	246.1007
Grade	Reference Standard
HSN code	38229090
InChIKey	YBJHBAHKTGYVGT-OXQHWPBHSA-N
SMILES	[2H]C1([C@H]2[C@@H]([C@@H](S1)CCCCC(=O)O)NC(=O)N2)[2H]
PubChem CID	60145986

Physical properties
Physical form	Solid
LogP (XLogP3)	0.3
H-bond donors / acceptors	3 / 4
TPSA	104 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Biotin-d2?

The CAS Registry Number of Biotin-d2 is 1217481-41-8. It is also known as Biotin-d2-1, Biotin-[D2] (Vitamin H-[D2]), Biotin-[2H2] (Vitamin H).

What is the molecular formula and molecular weight of Biotin-d2?

Biotin-d2 has the molecular formula C10H16N2O3S and a molecular weight of 246.33 g/mol. Its IUPAC name is 5-[(3aR,6S,6aS)-4,4-dideuterio-2-oxo-3,3a,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]pentanoic acid.

What is Biotin-d2 used for?

Biotin-d2 is supplied as a characterised reference material related to Biotin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Biotin-d2 can I order?

We supply Biotin-d2 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Biotin-d2?

Yes. Every lot of Biotin-d2 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Biotin-d2 be shipped internationally?

Yes. We export Biotin-d2 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.