Hydroxy Dabrafenib

Name: Hydroxy Dabrafenib
Brand: Vaqora Chemicals
SKU: VQ-022295

About Hydroxy Dabrafenib

Vaqora Chemicals supplies Hydroxy Dabrafenib, a metabolite or degradation product of Dabrafenib registered under CAS number 1195767-77-1. Its molecular formula is C23H20F3N5O3S2 and its molecular weight is 535.6 g/mol. Alternative names: Dabrafenib metabolite M7.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Dabrafenib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Hydroxy Dabrafenib in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Dabrafenib

View every impurity, metabolite and intermediate we list for Dabrafenib.

Dabrafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Hydroxy Dabrafenib
Catalogue No.	VQ-022295
CAS Number	1195767-77-1
IUPAC name	N-[3-[5-(2-aminopyrimidin-4-yl)-2-(1-hydroxy-2-methylpropan-2-yl)-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide
Molecular formula	C₂₃H₂₀F₃N₅O₃S₂
Molecular weight	535.6 g/mol
Exact mass	535.096
Grade	Reference Standard
HSN code	38229090
InChIKey	XUORVRVRUPDXCP-UHFFFAOYSA-N
SMILES	CC(C)(CO)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F
PubChem CID	57989740

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	3 / 12
TPSA	168 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydroxy Dabrafenib?

The CAS Registry Number of Hydroxy Dabrafenib is 1195767-77-1. It is also known as Dabrafenib metabolite M7.

What is the molecular formula and molecular weight of Hydroxy Dabrafenib?

Hydroxy Dabrafenib has the molecular formula C23H20F3N5O3S2 and a molecular weight of 535.6 g/mol. Its IUPAC name is N-[3-[5-(2-aminopyrimidin-4-yl)-2-(1-hydroxy-2-methylpropan-2-yl)-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide.

What is Hydroxy Dabrafenib used for?

Hydroxy Dabrafenib is supplied as a characterised reference material related to Dabrafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydroxy Dabrafenib can I order?

We supply Hydroxy Dabrafenib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydroxy Dabrafenib?

Yes. Every lot of Hydroxy Dabrafenib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydroxy Dabrafenib be shipped internationally?

Yes. We export Hydroxy Dabrafenib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.