Chlorthalidone USP

Name: Chlorthalidone USP
Brand: Vaqora Chemicals
SKU: VQ-007387

About Chlorthalidone USP

Chlorthalidone USP (CAS 77-36-1) is a high-purity reference standard of Chlorthalidone offered by Vaqora Chemicals. With the molecular formula C14H11ClN2O4S, it has a molar mass of 338.8 g/mol. The IUPAC name is 2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide. It is also known as Chlorthalidon or Chlorthalidone.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Chlorthalidone, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Chlorthalidone USP is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Chlorthalidone

View every impurity, metabolite and intermediate we list for Chlorthalidone.

Chlorthalidone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Chlorthalidone USP
Catalogue No.	VQ-007387
CAS Number	77-36-1
IUPAC name	2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide
Molecular formula	C₁₄H₁₁ClN₂O₄S
Molecular weight	338.8 g/mol
Exact mass	338.0128
Grade	Reference Standard
HSN code	38229090
InChIKey	JIVPVXMEBJLZRO-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C(=O)NC2(C3=CC(=C(C=C3)Cl)S(=O)(=O)N)O
PubChem CID	2732

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	3 / 5
TPSA	118 Å²
Synonyms	2-Chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)-benzenesulfonamide, 3-Hydroxy-3-[4-chloro-3-sulfamylphenyl]phthalimidine, Chlorthalidon, Chlorthalidone, Hygroton, Igroton, Phthalamudine, Zambesil, Natriuran, Oradil, Oxodolin, Racemic chlorthalidone

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 77-36-1

IP/BP/USP

Chlorthalidone

CAS: 77-36-1
Formula: C₁₄H₁₁ClN₂O₄S
MW: 338.8 g/mol

VQ-004086

Frequently asked questions

What is the CAS number of Chlorthalidone USP?

The CAS Registry Number of Chlorthalidone USP is 77-36-1. It is also known as 2-Chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)-benzenesulfonamide, 3-Hydroxy-3-[4-chloro-3-sulfamylphenyl]phthalimidine, Chlorthalidon.

What is the molecular formula and molecular weight of Chlorthalidone USP?

Chlorthalidone USP has the molecular formula C14H11ClN2O4S and a molecular weight of 338.8 g/mol. Its IUPAC name is 2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide.

What is Chlorthalidone USP used for?

Chlorthalidone USP is supplied as a characterised reference material related to Chlorthalidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Chlorthalidone USP can I order?

We supply Chlorthalidone USP in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Chlorthalidone USP?

Yes. Every lot of Chlorthalidone USP is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Chlorthalidone USP be shipped internationally?

Yes. Chlorthalidone USP is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.