Chlorthalidone

Name: Chlorthalidone
Brand: Vaqora Chemicals
SKU: VQ-004086

About Chlorthalidone

Chlorthalidone (CAS 77-36-1) is a cardiovascular API offered by Vaqora Chemicals in IP/BP/USP grade. Formula C14H11ClN2O4S, molecular weight 338.8 g/mol. The IUPAC name is 2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide. It is also known as Chlortalidone or Phthalamudine.

It is supplied as a white crystalline powder. Store in a tightly closed container in a cool, dry and well-ventilated place. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This API belongs to our cardiovascular and antihypertensive APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. Our customers for this product work in pharmaceutical manufacturing.

Vaqora Chemicals supplies Chlorthalidone in 1 kg, 5 kg and 25 kg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Chlorthalidone

View every impurity, metabolite and intermediate we list for Chlorthalidone.

Chlorthalidone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Chlorthalidone
Catalogue No.	VQ-004086
CAS Number	77-36-1
IUPAC name	2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide
Molecular formula	C₁₄H₁₁ClN₂O₄S
Molecular weight	338.8 g/mol
Exact mass	338.0128
Grade	IP/BP/USP
HSN code	2933
InChIKey	JIVPVXMEBJLZRO-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C(=O)NC2(C3=CC(=C(C=C3)Cl)S(=O)(=O)N)O
PubChem CID	2732

Physical properties
Physical form	Powder
Appearance	White crystalline powder
LogP (XLogP3)	0.9
H-bond donors / acceptors	3 / 5
TPSA	118 Å²
Synonyms	Chlortalidone, Phthalamudine, Chlorphthalidolone, Phthalamodine, Thalitone, Chlorothalidone, Chlorphthalidone, Saluretin, Clortalidone, 2-Chloro-5-(1-hydroxy-3-oxo-1-isoindolinyl)benzenesulfonamide, 3-Hydroxy-3-(4-chloro-3-sulfamylphenyl)phthalimidine, 3-(4'-Chloro-3'-sulfamoylphenyl)-3-hydroxyphthalimidine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 77-36-1

Reference Standard

Chlorthalidone USP

CAS: 77-36-1
Formula: C₁₄H₁₁ClN₂O₄S
MW: 338.8 g/mol

In stock

Frequently asked questions

What is the CAS number of Chlorthalidone?

The CAS Registry Number of Chlorthalidone is 77-36-1. It is also known as Chlortalidone, Phthalamudine, Chlorphthalidolone.

What is the molecular formula and molecular weight of Chlorthalidone?

Chlorthalidone has the molecular formula C14H11ClN2O4S and a molecular weight of 338.8 g/mol. Its IUPAC name is 2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide.

What is Chlorthalidone used for?

Chlorthalidone is supplied as a characterised reference material related to Chlorthalidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Chlorthalidone can I order?

We supply Chlorthalidone in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Chlorthalidone?

Yes. Every lot of Chlorthalidone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Chlorthalidone be shipped internationally?

Yes. Chlorthalidone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.