Cimetidine EP Impurity E

Name: Cimetidine EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-021153

About Cimetidine EP Impurity E

Cimetidine EP Impurity E (CAS 54237-72-8) is a pharmacopeial impurity of Cimetidine offered by Vaqora Chemicals. Formula C10H16N6OS, molecular weight 268.34 g/mol. Its systematic (IUPAC) name is 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfinyl]ethyl]guanidine. Alternative names: Cimetidine Hydrochloride - Impurity E and Cimetidine sulfoxide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Cimetidine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Cimetidine EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Cimetidine

View every impurity, metabolite and intermediate we list for Cimetidine.

Cimetidine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Cimetidine EP Impurity E
Catalogue No.	VQ-021153
CAS Number	54237-72-8
IUPAC name	1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfinyl]ethyl]guanidine
Molecular formula	C₁₀H₁₆N₆OS
Molecular weight	268.34 g/mol
Exact mass	268.1106
Grade	Reference Standard
HSN code	38229090
InChIKey	HOJLJLYVNQFCRE-UHFFFAOYSA-N
SMILES	CC1=C(N=CN1)CS(=O)CCNC(=NC)NC#N
PubChem CID	62949

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.1
H-bond donors / acceptors	3 / 5
TPSA	125 Å²
Synonyms	Cimetidine Hydrochloride - Impurity E, Cimetidine sulfoxide, 1-cyano-2-methyl-3-(2-(((4-methyl-1H-imidazol-5-yl)methyl)sulfinyl)ethyl)guanidine, Guanidine, N''-cyano-N-methyl-N'-(2-(((5-methyl-1H-imidazol-4-yl)methyl)sulfinyl)ethyl)-, cimetidine S-oxide, 1-Cyano-3-methyl-2-(2-(((4-methyl-1H-imidazol-5-yl)methyl)sulfinyl)ethyl)guanidine, Cimetidine sulfoxide, (+)-, (-)-Cimetidine S-oxide, Cimetidine sulfoxide, (-)-, 2-cyano-1-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfinyl}ethyl)guanidine, 2-Cyano-1-methyl-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfinyl]-ethyl]guanidine, Cimetidine impurity E

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H351Suspected of causing cancer
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cimetidine EP Impurity E?

The CAS Registry Number of Cimetidine EP Impurity E is 54237-72-8. It is also known as Cimetidine Hydrochloride - Impurity E, Cimetidine sulfoxide, 1-cyano-2-methyl-3-(2-(((4-methyl-1H-imidazol-5-yl)methyl)sulfinyl)ethyl)guanidine.

What is the molecular formula and molecular weight of Cimetidine EP Impurity E?

Cimetidine EP Impurity E has the molecular formula C10H16N6OS and a molecular weight of 268.34 g/mol. Its IUPAC name is 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfinyl]ethyl]guanidine.

What is Cimetidine EP Impurity E used for?

Cimetidine EP Impurity E is supplied as a characterised reference material related to Cimetidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cimetidine EP Impurity E can I order?

We supply Cimetidine EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cimetidine EP Impurity E?

Yes. Every lot of Cimetidine EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cimetidine EP Impurity E be shipped internationally?

Yes. Cimetidine EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.