Dapagliflozin USP Related Compound A

Name: Dapagliflozin USP Related Compound A
Brand: Vaqora Chemicals
SKU: VQ-006316

About Dapagliflozin USP Related Compound A

Dapagliflozin USP Related Compound A is a pharmacopeial impurity of Dapagliflozin carrying the CAS registry number 1807632-95-6 with a typical assay of 95.5%. With the molecular formula C21H25BrO6, it has a molar mass of 453.3 g/mol. The IUPAC name is (2S,3R,4R,5S,6R)-2-[4-bromo-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol. Alternative names: Dapagliflozin-4-Bromo Analog and 4-Deschloro-4-bromo Dapagliflozin.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Dapagliflozin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Dapagliflozin USP Related Compound A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Dapagliflozin

View every impurity, metabolite and intermediate we list for Dapagliflozin.

Dapagliflozin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Dapagliflozin USP Related Compound A
Catalogue No.	VQ-006316
CAS Number	1807632-95-6
IUPAC name	(2S,3R,4R,5S,6R)-2-[4-bromo-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
Molecular formula	C₂₁H₂₅BrO₆
Molecular weight	453.3 g/mol
Exact mass	452.0835
Grade	Reference Standard
Purity / assay	95.5%
HSN code	38229090
InChIKey	UABOQFANGSVXKK-ADAARDCZSA-N
SMILES	CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)Br
PubChem CID	126503386

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	4 / 6
TPSA	99.4 Å²
Synonyms	(1S)-1,5-Anhydro-1-C-[4-bromo-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol, Dapagliflozin-4-Bromo Analog, 4-Deschloro-4-bromo Dapagliflozin, (1S)-1,5-Anhydro-1-C-(4-bromo-3-((4-ethoxyphenyl)methyl)phenyl)-D-glucitol, D-Glucitol, 1,5-anhydro-1-C-[4-bromo-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, Dapagliflozin 4-Bromo Analog, Dapagliflozin-8, Dapagliflozin IMP, Dapagliflozin alpha-Isomer

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation
H372Causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P260, P264, P264 + P265, P270, P273, P280, P301 + P317, P305 + P351 + P338, P319, P330, P337 + P317, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dapagliflozin USP Related Compound A?

The CAS Registry Number of Dapagliflozin USP Related Compound A is 1807632-95-6. It is also known as (1S)-1,5-Anhydro-1-C-[4-bromo-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol, Dapagliflozin-4-Bromo Analog, 4-Deschloro-4-bromo Dapagliflozin.

What is the molecular formula and molecular weight of Dapagliflozin USP Related Compound A?

Dapagliflozin USP Related Compound A has the molecular formula C21H25BrO6 and a molecular weight of 453.3 g/mol. Its IUPAC name is (2S,3R,4R,5S,6R)-2-[4-bromo-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol.

What is Dapagliflozin USP Related Compound A used for?

Dapagliflozin USP Related Compound A is supplied as a characterised reference material related to Dapagliflozin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dapagliflozin USP Related Compound A can I order?

We supply Dapagliflozin USP Related Compound A in Reference Standard (95.5%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dapagliflozin USP Related Compound A?

Yes. Every lot of Dapagliflozin USP Related Compound A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dapagliflozin USP Related Compound A be shipped internationally?

Yes. Dapagliflozin USP Related Compound A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.