Defluoro O-Methyl Dolutegravir

Name: Defluoro O-Methyl Dolutegravir
Brand: Vaqora Chemicals
SKU: VQ-036778

About Defluoro O-Methyl Dolutegravir

Listed under CAS 2244245-33-6, Defluoro O-Methyl Dolutegravir is an impurity of Dolutegravir available from Vaqora Chemicals. Its molecular formula is C21H22FN3O5 and its molecular weight is 415.4 g/mol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Dolutegravir, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Defluoro O-Methyl Dolutegravir in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dolutegravir

View every impurity, metabolite and intermediate we list for Dolutegravir.

Dolutegravir impurities

Specifications & identifiers

Chemical identifiers
Product name	Defluoro O-Methyl Dolutegravir
Catalogue No.	VQ-036778
CAS Number	2244245-33-6
IUPAC name	(3S,7R)-N-[(4-fluorophenyl)methyl]-11-methoxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide
Molecular formula	C₂₁H₂₂FN₃O₅
Molecular weight	415.4 g/mol
Exact mass	415.1543
Grade	Reference Standard
HSN code	38229090
InChIKey	PGTXEQHVCFMSMI-WBMJQRKESA-N
SMILES	C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=CC=C(C=C4)F)OC
PubChem CID	169437205

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	1 / 7
TPSA	88.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Defluoro O-Methyl Dolutegravir?

The CAS Registry Number of Defluoro O-Methyl Dolutegravir is 2244245-33-6.

What is the molecular formula and molecular weight of Defluoro O-Methyl Dolutegravir?

Defluoro O-Methyl Dolutegravir has the molecular formula C21H22FN3O5 and a molecular weight of 415.4 g/mol. Its IUPAC name is (3S,7R)-N-[(4-fluorophenyl)methyl]-11-methoxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide.

What is Defluoro O-Methyl Dolutegravir used for?

Defluoro O-Methyl Dolutegravir is supplied as a characterised reference material related to Dolutegravir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Defluoro O-Methyl Dolutegravir can I order?

We supply Defluoro O-Methyl Dolutegravir in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Defluoro O-Methyl Dolutegravir?

Yes. Every lot of Defluoro O-Methyl Dolutegravir is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Defluoro O-Methyl Dolutegravir be shipped internationally?

Yes. We export Defluoro O-Methyl Dolutegravir worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.