Desmethyl Bosentan

Name: Desmethyl Bosentan
Brand: Vaqora Chemicals
SKU: VQ-020975

About Desmethyl Bosentan

Desmethyl Bosentan is a metabolite or degradation product of Bosentan carrying the CAS registry number 253688-61-8. With the molecular formula C26H27N5O6S, it has a molar mass of 537.6 g/mol. Its systematic (IUPAC) name is 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide. It is also known as O-Desmethyl Bosentan.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Bosentan, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Desmethyl Bosentan in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Bosentan

View every impurity, metabolite and intermediate we list for Bosentan.

Bosentan impurities

Specifications & identifiers

Chemical identifiers
Product name	Desmethyl Bosentan
Catalogue No.	VQ-020975
CAS Number	253688-61-8
IUPAC name	4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
Molecular formula	C₂₆H₂₇N₅O₆S
Molecular weight	537.6 g/mol
Exact mass	537.1682
Grade	Reference Standard
HSN code	38229090
InChIKey	STTLKJGYAWXIPP-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4O
PubChem CID	6426756

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	3 / 11
TPSA	165 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Desmethyl Bosentan?

The CAS Registry Number of Desmethyl Bosentan is 253688-61-8. It is also known as O-Desmethyl Bosentan.

What is the molecular formula and molecular weight of Desmethyl Bosentan?

Desmethyl Bosentan has the molecular formula C26H27N5O6S and a molecular weight of 537.6 g/mol. Its IUPAC name is 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide.

What is Desmethyl Bosentan used for?

Desmethyl Bosentan is supplied as a characterised reference material related to Bosentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Desmethyl Bosentan can I order?

We supply Desmethyl Bosentan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Desmethyl Bosentan?

Yes. Every lot of Desmethyl Bosentan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Desmethyl Bosentan be shipped internationally?

Yes. We export Desmethyl Bosentan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.