Bosentan USP Related Compound A

Name: Bosentan USP Related Compound A
Brand: Vaqora Chemicals
SKU: VQ-021865

About Bosentan USP Related Compound A

Bosentan USP Related Compound A (CAS 150727-06-3) is a pharmacopeial impurity of Bosentan offered by Vaqora Chemicals. Formula C25H24ClN5O4S, molecular weight 526.0 g/mol. Systematically, it is named 4-tert-butyl-N-[6-chloro-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide. Alternative names: Bosentan Chloro intermediate and Bosentan Related Compound A.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Bosentan, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Bosentan USP Related Compound A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Bosentan

View every impurity, metabolite and intermediate we list for Bosentan.

Bosentan impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Bosentan USP Related Compound A
Catalogue No.	VQ-021865
CAS Number	150727-06-3
IUPAC name	4-tert-butyl-N-[6-chloro-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
Molecular formula	C₂₅H₂₄ClN₅O₄S
Molecular weight	526 g/mol
Exact mass	525.1238
Grade	Reference Standard
HSN code	38229090
InChIKey	XKISWHVJIZSPSC-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)Cl)OC4=CC=CC=C4OC
PubChem CID	11135160

Physical properties
Physical form	Solid
LogP (XLogP3)	5.2
H-bond donors / acceptors	1 / 9
TPSA	125 Å²
Synonyms	Bosentan Chloro intermediate, Bosentan Related Compound A, 4-Tert-butyl-n-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide, 4-Tert-Butyl-N-(6-Chloro-5-(2-Methoxyphenoxy)-2,2-Bipyrimidin-4-yl)Benzenesulfonamide, Bosentn related compound A, CS-M1819, 4-(tert-butyl)-N-(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide, 4-tert-Butyl-N-[6-chloro-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzene-1-sulfonamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bosentan USP Related Compound A?

The CAS Registry Number of Bosentan USP Related Compound A is 150727-06-3. It is also known as Bosentan Chloro intermediate, Bosentan Related Compound A, 4-Tert-butyl-n-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide.

What is the molecular formula and molecular weight of Bosentan USP Related Compound A?

Bosentan USP Related Compound A has the molecular formula C25H24ClN5O4S and a molecular weight of 526 g/mol. Its IUPAC name is 4-tert-butyl-N-[6-chloro-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide.

What is Bosentan USP Related Compound A used for?

Bosentan USP Related Compound A is supplied as a characterised reference material related to Bosentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bosentan USP Related Compound A can I order?

We supply Bosentan USP Related Compound A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bosentan USP Related Compound A?

Yes. Every lot of Bosentan USP Related Compound A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bosentan USP Related Compound A be shipped internationally?

Yes. Bosentan USP Related Compound A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.