Hydroxy Desmethyl Bosentan

Name: Hydroxy Desmethyl Bosentan
Brand: Vaqora Chemicals
SKU: VQ-024086

About Hydroxy Desmethyl Bosentan

Hydroxy Desmethyl Bosentan is a metabolite or degradation product of Bosentan carrying the CAS registry number 253688-62-9. Formula C26H27N5O7S, molecular weight 553.6 g/mol. It is also known as Hydroxy O-Desmethyl Bosentan or Hydroxy-demethoxybosentan.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Bosentan, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Hydroxy Desmethyl Bosentan in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Bosentan

View every impurity, metabolite and intermediate we list for Bosentan.

Bosentan impurities

Specifications & identifiers

Chemical identifiers
Product name	Hydroxy Desmethyl Bosentan
Catalogue No.	VQ-024086
CAS Number	253688-62-9
IUPAC name	N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide
Molecular formula	C₂₆H₂₇N₅O₇S
Molecular weight	553.6 g/mol
Exact mass	553.1631
Grade	Reference Standard
HSN code	38229090
InChIKey	JXXCMZWROOURSZ-UHFFFAOYSA-N
SMILES	CC(C)(CO)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4O
PubChem CID	6426757

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	4 / 12
TPSA	185 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydroxy Desmethyl Bosentan?

The CAS Registry Number of Hydroxy Desmethyl Bosentan is 253688-62-9. It is also known as Hydroxy O-Desmethyl Bosentan, Hydroxy-demethoxybosentan.

What is the molecular formula and molecular weight of Hydroxy Desmethyl Bosentan?

Hydroxy Desmethyl Bosentan has the molecular formula C26H27N5O7S and a molecular weight of 553.6 g/mol. Its IUPAC name is N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide.

What is Hydroxy Desmethyl Bosentan used for?

Hydroxy Desmethyl Bosentan is supplied as a characterised reference material related to Bosentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydroxy Desmethyl Bosentan can I order?

We supply Hydroxy Desmethyl Bosentan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydroxy Desmethyl Bosentan?

Yes. Every lot of Hydroxy Desmethyl Bosentan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydroxy Desmethyl Bosentan be shipped internationally?

Yes. We export Hydroxy Desmethyl Bosentan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.