Dexamethasone EP impurity C

Name: Dexamethasone EP impurity C
Brand: Vaqora Chemicals
SKU: VQ-022340

About Dexamethasone EP impurity C

Dexamethasone EP impurity C (CAS 426-17-5) is a pharmacopeial impurity of Dexamethasone offered by Vaqora Chemicals. Its molecular formula is C22H31FO5 and its molecular weight is 394.5 g/mol. It is also known as Dexamethasone - Impurity C or 1,2-Dihydro Dexamethasone.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Dexamethasone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Dexamethasone EP impurity C is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Dexamethasone

View every impurity, metabolite and intermediate we list for Dexamethasone.

Dexamethasone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Dexamethasone EP impurity C
Catalogue No.	VQ-022340
CAS Number	426-17-5
IUPAC name	(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Molecular formula	C₂₂H₃₁FO₅
Molecular weight	394.5 g/mol
Exact mass	394.2156
Grade	Reference Standard
HSN code	38229090
InChIKey	YYZXYYHUGHQGHI-CXSFZGCWSA-N
SMILES	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C
PubChem CID	22792547

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	3 / 6
TPSA	94.8 Å²
Synonyms	Dexamethasone - Impurity C, 1,2-Dihydro Dexamethasone, 9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregn-4-ene-3,20-dione, Pregn-4-ene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-, Pregn-4-ene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11beta,16alpha)-, (11beta,16alpha)-9-Fluoro-11,17,21-trihydroxy-16-methylpregn-4-ene-3,20-dione, US10188667, Dexamethasone, (11, A,16, A)-9-Fluoro-11,17,21-trihydroxy-16-methylpregn-4-ene-3,20-dione, 9-Fluoro-11,17,21-trihydroxy-16-methylpregn-4-ene-3,20-dione

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P264, P270, P301 + P317, P319, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dexamethasone EP impurity C?

The CAS Registry Number of Dexamethasone EP impurity C is 426-17-5. It is also known as Dexamethasone - Impurity C, 1,2-Dihydro Dexamethasone, 9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregn-4-ene-3,20-dione.

What is the molecular formula and molecular weight of Dexamethasone EP impurity C?

Dexamethasone EP impurity C has the molecular formula C22H31FO5 and a molecular weight of 394.5 g/mol.

What is Dexamethasone EP impurity C used for?

Dexamethasone EP impurity C is supplied as a characterised reference material related to Dexamethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dexamethasone EP impurity C can I order?

We supply Dexamethasone EP impurity C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dexamethasone EP impurity C?

Yes. Every lot of Dexamethasone EP impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dexamethasone EP impurity C be shipped internationally?

Yes. Dexamethasone EP impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.