Duvelisib

Name: Duvelisib
Brand: Vaqora Chemicals
SKU: VQ-030345

About Duvelisib

Listed under CAS 1201438-56-3, Duvelisib is a high-purity reference standard of Duvelisib available from Vaqora Chemicals. The compound has the formula C22H17ClN6O, corresponding to a molecular weight of 416.9 g/mol. Systematically, it is named 8-chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-one. It is also known as IPI-145 or INK-1197.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Duvelisib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Duvelisib

View every impurity, metabolite and intermediate we list for Duvelisib.

Duvelisib impurities

Specifications & identifiers

Chemical identifiers
Product name	Duvelisib
Catalogue No.	VQ-030345
CAS Number	1201438-56-3
IUPAC name	8-chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-one
Molecular formula	C₂₂H₁₇ClN₆O
Molecular weight	416.9 g/mol
Exact mass	416.1152
Grade	Reference Standard
HSN code	38229090
InChIKey	SJVQHLPISAIATJ-ZDUSSCGKSA-N
SMILES	C[C@@H](C1=CC2=C(C(=CC=C2)Cl)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
PubChem CID	50905713

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	2 / 5
TPSA	86.8 Å²
Synonyms	IPI-145, INK-1197, (S)-3-(1-((9H-Purin-6-yl)amino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one, IPI 145, (S)-3-(1-(9H-purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one, INK-1147, 1(2H)-Isoquinolinone, 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-, 8-Chloro-2-phenyl-3-((1S)-1-(7H-purin-6-ylamino)ethyl)isoquinolin-1(2H)-one, 1(2H)-Isoquinolinone, 8-chloro-2-phenyl-3-((1S)-1-(9H-purin-6-ylamino)ethyl)-, 8-chloro-2-phenyl-3-((1S)-1-((9H-purin-6-yl)amino)ethyl)-1,2-dihydroisoquinolin-1-one, 8-chloro-2-phenyl-3-[(1S)-1-[(9H-purin-6-yl)amino]ethyl]-1,2-dihydroisoquinolin-1-one, Duvelisib (IPI-145, INK1197)

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H360May damage fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Duvelisib?

The CAS Registry Number of Duvelisib is 1201438-56-3. It is also known as IPI-145, INK-1197, (S)-3-(1-((9H-Purin-6-yl)amino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one.

What is the molecular formula and molecular weight of Duvelisib?

Duvelisib has the molecular formula C22H17ClN6O and a molecular weight of 416.9 g/mol. Its IUPAC name is 8-chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-one.

What is Duvelisib used for?

Duvelisib is supplied as a characterised reference material related to Duvelisib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Duvelisib can I order?

We supply Duvelisib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Duvelisib?

Yes. Every lot of Duvelisib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Duvelisib be shipped internationally?

Yes. Duvelisib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.