(E)-3-Cyclopentylacrylonitrile

Name: (E)-3-Cyclopentylacrylonitrile
Brand: Vaqora Chemicals
SKU: VQ-012771

About (E)-3-Cyclopentylacrylonitrile

(E)-3-Cyclopentylacrylonitrile is a process intermediate or related compound of Ruxolitinib carrying the CAS registry number 1236033-37-6. Its molecular formula is C8H11N and its molecular weight is 121.18 g/mol. Its systematic (IUPAC) name is (E)-3-cyclopentylprop-2-enenitrile. Alternative names: (2E)-3-Cyclopentyl-2-propenenitrile and (2E)-3-Cyclopentylacrylonitrile.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Ruxolitinib, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Ruxolitinib

View every impurity, metabolite and intermediate we list for Ruxolitinib.

Ruxolitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	(E)-3-Cyclopentylacrylonitrile
Catalogue No.	VQ-012771
CAS Number	1236033-37-6
Other CAS	591769-05-0
IUPAC name	(E)-3-cyclopentylprop-2-enenitrile
Molecular formula	C₈H₁₁N
Molecular weight	121.18 g/mol
Exact mass	121.0891
Grade	Reference Standard
HSN code	2933
InChIKey	VMELXYJYSXXORF-ZZXKWVIFSA-N
SMILES	C1CCC(C1)/C=C/C#N
PubChem CID	21427952

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	0 / 1
TPSA	23.8 Å²
Synonyms	(2E)-3-Cyclopentyl-2-propenenitrile, (2E)-3-Cyclopentylacrylonitrile, (E)-3-Cyclopentyl-2-propenenitrile, (2E)-3-cyclopentylprop-2-enenitrile, 3-Cyclopentylacrylonitrile, 3-cyclopentylprop-2-enenitrile, 3-(Cyclopentyl)prop-2-enenitrile, 3-Cyclopentylacrylonitrile, AldrichCPR

Safety & hazard information (GHS)

Corrosive

Toxic

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H227Combustible liquid
H301Toxic if swallowed
H311Toxic in contact with skin
H314Causes severe skin burns and eye damage
H331Toxic if inhaled
H351Suspected of causing cancer
H411Toxic to aquatic life with long lasting effects
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P210, P260, P261, P262, P264, P270, P271, P273, P280, P301 + P316, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P318, P321, P330, P361 + P364, P363, P370 + P378, P391

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (E)-3-Cyclopentylacrylonitrile?

The CAS Registry Number of (E)-3-Cyclopentylacrylonitrile is 1236033-37-6. It is also known as (2E)-3-Cyclopentyl-2-propenenitrile, (2E)-3-Cyclopentylacrylonitrile, (E)-3-Cyclopentyl-2-propenenitrile.

What is the molecular formula and molecular weight of (E)-3-Cyclopentylacrylonitrile?

(E)-3-Cyclopentylacrylonitrile has the molecular formula C8H11N and a molecular weight of 121.18 g/mol. Its IUPAC name is (E)-3-cyclopentylprop-2-enenitrile.

What is (E)-3-Cyclopentylacrylonitrile used for?

(E)-3-Cyclopentylacrylonitrile is supplied as a characterised reference material related to Ruxolitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (E)-3-Cyclopentylacrylonitrile can I order?

We supply (E)-3-Cyclopentylacrylonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (E)-3-Cyclopentylacrylonitrile?

Yes. Every lot of (E)-3-Cyclopentylacrylonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (E)-3-Cyclopentylacrylonitrile be shipped internationally?

Yes. (E)-3-Cyclopentylacrylonitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.