4-Amino-6-chloropyrimidine-5-carbaldehyde
Synonyms: 4-Amino-6-chloro-5-pyrimidinecarboxaldehyde · 6-Chloro-5-difluoromethyl-pyrimidin-4-ylamine · 4-Amino-6-chloropyrimidine-5-carboxaldehyde · 5-Pyrimidinecarboxaldehyde, 4-amino-6-chloro-
4-Amino-6-chloropyrimidine-5-carbaldehyde (CAS 14160-93-1) – Ruxolitinib intermediate. C5H4ClN3O, MW 157.56. Vaqora Chemicals: COA, global shipping.
About 4-Amino-6-chloropyrimidine-5-carbaldehyde
Listed under CAS 14160-93-1, 4-Amino-6-chloropyrimidine-5-carbaldehyde is a process intermediate or related compound of Ruxolitinib available from Vaqora Chemicals. With the molecular formula C5H4ClN3O, it has a molar mass of 157.56 g/mol. Common synonyms include 4-Amino-6-chloro-5-pyrimidinecarboxaldehyde and 6-Chloro-5-difluoromethyl-pyrimidin-4-ylamine.
It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.
Process chemists and analysts use it when developing synthetic routes to Ruxolitinib, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-Amino-6-chloropyrimidine-5-carbaldehyde is dispatched with a Certificate of Analysis (COA) to destinations worldwide.
Typical applications
- API route development
- Impurity fate & purge studies
- Analytical method development
Industries
View every impurity, metabolite and intermediate we list for Ruxolitinib.
Ruxolitinib impuritiesSpecifications & identifiers
| Product name | 4-Amino-6-chloropyrimidine-5-carbaldehyde |
|---|---|
| Catalogue No. | VQ-013081 |
| CAS Number | 14160-93-1 |
| IUPAC name | 4-amino-6-chloropyrimidine-5-carbaldehyde |
| Molecular formula | C5H4ClN3O |
| Molecular weight | 157.56 g/mol |
| Exact mass | 157.0043 |
| Grade | Reference Standard |
| HSN code | 2933 |
| InChIKey | GOJNFUXEBVBARW-UHFFFAOYSA-N |
| SMILES | C1=NC(=C(C(=N1)Cl)C=O)N |
| PubChem CID | 84230 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 0.8 |
| H-bond donors / acceptors | 1 / 4 |
| TPSA | 68.9 Ų |
| Synonyms | 4-Amino-6-chloro-5-pyrimidinecarboxaldehyde, 6-Chloro-5-difluoromethyl-pyrimidin-4-ylamine, 4-Amino-6-chloropyrimidine-5-carboxaldehyde, 5-Pyrimidinecarboxaldehyde, 4-amino-6-chloro-, 4-Amino-6-chloro-5-pyrimidinecarbaldehyde, 6-amino-4-chloropyrimidine-5-carbaldehyde |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H315Causes skin irritationH319Causes serious eye irritationH335May cause respiratory irritation
Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of 4-Amino-6-chloropyrimidine-5-carbaldehyde?
The CAS Registry Number of 4-Amino-6-chloropyrimidine-5-carbaldehyde is 14160-93-1. It is also known as 4-Amino-6-chloro-5-pyrimidinecarboxaldehyde, 6-Chloro-5-difluoromethyl-pyrimidin-4-ylamine, 4-Amino-6-chloropyrimidine-5-carboxaldehyde.
What is the molecular formula and molecular weight of 4-Amino-6-chloropyrimidine-5-carbaldehyde?
4-Amino-6-chloropyrimidine-5-carbaldehyde has the molecular formula C5H4ClN3O and a molecular weight of 157.56 g/mol. Its IUPAC name is 4-amino-6-chloropyrimidine-5-carbaldehyde.
What is 4-Amino-6-chloropyrimidine-5-carbaldehyde used for?
4-Amino-6-chloropyrimidine-5-carbaldehyde is supplied as a characterised reference material related to Ruxolitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of 4-Amino-6-chloropyrimidine-5-carbaldehyde can I order?
We supply 4-Amino-6-chloropyrimidine-5-carbaldehyde in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with 4-Amino-6-chloropyrimidine-5-carbaldehyde?
Yes. Every lot of 4-Amino-6-chloropyrimidine-5-carbaldehyde is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can 4-Amino-6-chloropyrimidine-5-carbaldehyde be shipped internationally?
Yes. 4-Amino-6-chloropyrimidine-5-carbaldehyde is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about 4-Amino-6-chloropyrimidine-5-carbaldehyde
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