(E/Z)-4-Hydroxy Tamoxifen

Name: (E/Z)-4-Hydroxy Tamoxifen
Brand: Vaqora Chemicals
SKU: VQ-042358

About (E/Z)-4-Hydroxy Tamoxifen

(E/Z)-4-Hydroxy Tamoxifen (CAS 68392-35-8) is a metabolite or degradation product of Tamoxifen offered by Vaqora Chemicals. Its molecular formula is C26H29NO2 and its molecular weight is 387.5 g/mol. The IUPAC name is 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol. Alternative names: 4-Hydroxy-tamoxifen and Afimoxifene.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 5 hazard statements. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Tamoxifen, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer (E/Z)-4-Hydroxy Tamoxifen in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Tamoxifen

View every impurity, metabolite and intermediate we list for Tamoxifen.

Tamoxifen impurities

Specifications & identifiers

Chemical identifiers
Product name	(E/Z)-4-Hydroxy Tamoxifen
Catalogue No.	VQ-042358
CAS Number	68392-35-8
IUPAC name	4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
Molecular formula	C₂₆H₂₉NO₂
Molecular weight	387.5 g/mol
Exact mass	387.2198
Grade	Reference Standard
HSN code	38229090
InChIKey	TXUZVZSFRXZGTL-UHFFFAOYSA-N
SMILES	CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
PubChem CID	63062

Physical properties
Physical form	Solid
LogP (XLogP3)	6.8
H-bond donors / acceptors	1 / 3
TPSA	32.7 Å²
Synonyms	4-Hydroxy-tamoxifen, 4-(1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenyl-1-buten-1-yl)phenol, 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol, Afimoxifene, (Z)-4-(1-(4-(2-(Dimethylamino)ethoxy)-phenyl)-2-phenylbut-1-en-1-yl)phenol, (Z)-4-Hydroxy Tamoxifen, 4-(1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol, 4-(1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl)phenol, 4-Hydroxytamoxifen (Afimoxifene), (Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol, Phenol, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]-

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P318, P321, P330, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (E/Z)-4-Hydroxy Tamoxifen?

The CAS Registry Number of (E/Z)-4-Hydroxy Tamoxifen is 68392-35-8. It is also known as 4-Hydroxy-tamoxifen, 4-(1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenyl-1-buten-1-yl)phenol, 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol.

What is the molecular formula and molecular weight of (E/Z)-4-Hydroxy Tamoxifen?

(E/Z)-4-Hydroxy Tamoxifen has the molecular formula C26H29NO2 and a molecular weight of 387.5 g/mol. Its IUPAC name is 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol.

What is (E/Z)-4-Hydroxy Tamoxifen used for?

(E/Z)-4-Hydroxy Tamoxifen is supplied as a characterised reference material related to Tamoxifen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (E/Z)-4-Hydroxy Tamoxifen can I order?

We supply (E/Z)-4-Hydroxy Tamoxifen in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (E/Z)-4-Hydroxy Tamoxifen?

Yes. Every lot of (E/Z)-4-Hydroxy Tamoxifen is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (E/Z)-4-Hydroxy Tamoxifen be shipped internationally?

Yes. (E/Z)-4-Hydroxy Tamoxifen is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.